AutismKB 2.0

Annotation Details for ADRA1B


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Basic Information Top
Gene Symbol:ADRA1B ( ADRA1,ALPHA1BAR )
Gene Full Name: adrenergic, alpha-1B-, receptor
Band: 5q33.3
Quick LinksEntrez ID:147; OMIM: 104220; Uniprot ID:ADA1B_HUMAN; ENSEMBL ID: ENSG00000170214; HGNC ID: 278
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus22120526
GO:0005886IDA-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane1328250
GO:0031965IDA-nuclear membrane22120526
GO ID Evidence Qualifier GO_term References
GO:0004937IBA-alpha1-adrenergic receptor activity-
GO:0046982IDA-protein heterodimerization activity22120526
GO ID Evidence Qualifier GO_term References
GO:0001994IBA-norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure-
GO:0007186TAS-G-protein coupled receptor signaling pathway2154750
GO:0007188TAS-adenylate cyclase-modulating G-protein coupled receptor signaling pathway10820200
GO:0007200IBA-phospholipase C-activating G-protein coupled receptor signaling pathway-
GO:0007204IBA-positive regulation of cytosolic calcium ion concentration-
GO:0007267TAS-cell-cell signaling1328250
GO:0007275TAS-multicellular organism development10820200
GO:0008283TAS-cell proliferation10820200
GO:0035556TAS-intracellular signal transduction10820200
GO:0042593IBA-glucose homeostasis-
GO:0043410IDA-positive regulation of MAPK cascade22120526
GO:0045907IBA-positive regulation of vasoconstriction-
GO:0045987IBA-positive regulation of smooth muscle contraction-
GO:0055117IEA-regulation of cardiac muscle contraction-
GO:0071880IBA-adenylate cyclase-activating adrenergic receptor signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
AP2M1ADRA1B10758712644451 Affinity Capture-Western; Two-hybrid
AP2M1ADRA1B10665712644451 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104774
  • Data Attributes: MGI curated and HomoloGene calculated
No data