AutismKB 2.0

Annotation Details for CST3


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Basic Information Top
Gene Symbol:CST3 ( ARMD11,MGC117328 )
Gene Full Name: cystatin C
Band: 20p11.21
Quick LinksEntrez ID:1471; OMIM: 604312; Uniprot ID:CYTC_HUMAN; ENSEMBL ID: ENSG00000101439; HGNC ID: 2475
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576IMP-extracellular region18026102
GO:0005576TAS-extracellular region-
GO:0005604IEA-basement membrane-
GO:0005615IDA-extracellular space3488317
GO:0005764IEA-lysosome-
GO:0005771IEA-multivesicular body-
GO:0005788TAS-endoplasmic reticulum lumen-
GO:0030424IEA-axon-
GO:0031965IEA-nuclear membrane-
GO:0043025IEA-neuronal cell body-
GO:0043292IEA-contractile fiber-
GO:0048471IEA-perinuclear region of cytoplasm-
GO:0070062IDA-extracellular exosome19056867
GO:1904724TAS-tertiary granule lumen-
GO:1904813TAS-ficolin-1-rich granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0001540IPI-amyloid-beta binding18026102
GO:0002020IPI-protease binding6203523
GO:0004866IDA-endopeptidase inhibitor activity15127951
GO:0004869IDA-cysteine-type endopeptidase inhibitor activity3488317
GO:0005515IPI-protein binding15127951
GO:0042802IPI-identical protein binding25479090
GO ID Evidence Qualifier GO_term References
GO:0001654IEA-eye development-
GO:0001666IEA-response to hypoxia-
GO:0006915IEA-apoptotic process-
GO:0006952IDA-defense response6203523
GO:0007420IEA-brain development-
GO:0007431IEA-salivary gland development-
GO:0007566IEA-embryo implantation-
GO:0008284IEA-positive regulation of cell proliferation-
GO:0009636IEA-response to toxic substance-
GO:0009743IEA-response to carbohydrate-
GO:0010466IDA-negative regulation of peptidase activity6203523
GO:0010711IEP-negative regulation of collagen catabolic process10545518
GO:0010716IC-negative regulation of extracellular matrix disassembly7890620
GO:0010716IEP-negative regulation of extracellular matrix disassembly10545518
GO:0010951IEA-negative regulation of endopeptidase activity-
GO:0031667IEA-response to nutrient levels-
GO:0032355IEA-response to estradiol-
GO:0034103IEP-regulation of tissue remodeling10545518
GO:0042493IEA-response to drug-
GO:0042747IEA-circadian sleep/wake cycle, REM sleep-
GO:0043067IEA-regulation of programmed cell death-
GO:0043312TAS-neutrophil degranulation-
GO:0043687TAS-post-translational protein modification-
GO:0044267TAS-cellular protein metabolic process-
GO:0045740IEA-positive regulation of DNA replication-
GO:0045861IDA-negative regulation of proteolysis3488317
GO:0048678IEA-response to axon injury-
GO:0060009IEA-Sertoli cell development-
GO:0060311IMP-negative regulation of elastin catabolic process10545518
GO:0060313IEP-negative regulation of blood vessel remodeling10545518
GO:0060548IEA-negative regulation of cell death-
GO:0070301IEA-cellular response to hydrogen peroxide-
GO:0097435IGI-supramolecular fiber organization18026102
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CST3C4A1071812304899 Reconstituted Complex
CST3C4A1078532304899 Reconstituted Complex
CSTBCST31078531996959 Biochemical Activity
CSTBCST31078581996959 Biochemical Activity
CTSBCST310788814503883 Reconstituted Complex
CTSBCST310785314503883 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
CST3CST_5'UTR -72, rs1064039, rs2145231, rs2424577, rs3827143, rs5030707, rs6036478, rs911122 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:102519
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-373'