AutismKB 2.0

Annotation Details for CSTA


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Basic Information Top
Gene Symbol:CSTA ( STF1,STFA )
Gene Full Name: cystatin A (stefin A)
Band: 3q21.1
Quick LinksEntrez ID:1475; OMIM: 184600; Uniprot ID:CYTA_HUMAN; ENSEMBL ID: ENSG00000121552; HGNC ID: 2481
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001533IDA-cornified envelope10908733
GO:0001533TAS-cornified envelope-
GO:0005615IDA-extracellular space3488317
GO:0005737IDA-cytoplasm21944047
GO:0005829TAS-cytosol-
GO:0031012IDA-extracellular matrix23979707
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0002020IPI-protease binding6203523
GO:0004869IDA-cysteine-type endopeptidase inhibitor activity3488317
GO:0005198IDA-structural molecule activity10908733
GO:0030674IDA-protein binding, bridging10908733
GO ID Evidence Qualifier GO_term References
GO:0010466IDA-negative regulation of peptidase activity6203523
GO:0010951IEA-negative regulation of endopeptidase activity-
GO:0016337IMP-single organismal cell-cell adhesion21944047
GO:0018149IDA-peptide cross-linking10908733
GO:0030216IDA-keratinocyte differentiation10908733
GO:0045861IDA-negative regulation of proteolysis3488317
GO:0070268TAS-cornification-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DSPCSTA1081668999895 Reconstituted Complex
DSPCSTA1078578999895 Reconstituted Complex
IVLCSTA1099178999895 Reconstituted Complex
IVLCSTA1078578999895 Reconstituted Complex
KRT1CSTA1100468999895 Reconstituted Complex
KRT1CSTA1078578999895 Reconstituted Complex
LORCSTA1101988999895 Reconstituted Complex
LORCSTA1078578999895 Reconstituted Complex
PI3CSTA1112848999895 Reconstituted Complex
PI3CSTA1078578999895 Reconstituted Complex
CTSBCSTA1078889585570 14503883 Reconstituted Complex
CTSBCSTA1078579585570 14503883 Reconstituted Complex
CTSL1CSTA1078949585570 12921779 Reconstituted Complex
CTSL1CSTA1078579585570 12921779 Reconstituted Complex
CSTACSTA10785711532941 Reconstituted Complex
CTSHCSTA10789212581647 Co-crystal Structure
CTSHCSTA10785712581647 Co-crystal Structure
USP53CSTA12002019615732 Affinity Capture-MS
USP53CSTA10785719615732 Affinity Capture-MS
Gene Symbol Interactant Interaction ID References Description
CTSHCSTA1912012581647 Lysosomal cysteine protease cathepsin H interacts with intracellular protease inhibitor stefin A. This interaction is modeled based on a demonstrated interaction between porcine cathepsin H and human stefinA.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:3524930
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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