AutismKB 2.0

Annotation Details for CTBP1


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Basic Information Top
Gene Symbol:CTBP1 ( BARS,MGC104684 )
Gene Full Name: C-terminal binding protein 1
Band: 4p16.3
Quick LinksEntrez ID:1487; OMIM: 602618; Uniprot ID:CTBP1_HUMAN; ENSEMBL ID: ENSG00000159692; HGNC ID: 2494
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus16702210
GO:0005634ISS-nucleus-
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005667IEA-transcription factor complex-
GO:0005737IEA-cytoplasm-
GO:0017053IDA-transcriptional repressor complex16287852
GO:0017053ISS-transcriptional repressor complex-
GO ID Evidence Qualifier GO_term References
GO:0001106IDA-RNA polymerase II transcription corepressor activity16287852
GO:0003700IEA-transcription factor activity, sequence-specific DNA binding-
GO:0005515IPI-protein binding11568182
GO:0008022TAS-protein C-terminus binding8440238
GO:0008134IPI-transcription factor binding16609867
GO:0016616IEA-oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor-
GO:0019904IDA-protein domain specific binding19162039
GO:0019904IPI-protein domain specific binding18374649
GO:0051287ISS-NAD binding-
GO:0070491IPI-repressing transcription factor binding19162039
GO ID Evidence Qualifier GO_term References
GO:0000122IMP-negative regulation of transcription from RNA polymerase II promoter19162039
GO:0006351IEA-transcription, DNA-templated-
GO:0006468TAS-protein phosphorylation8440238
GO:0008285TAS-negative regulation of cell proliferation7479821
GO:0019079TAS-viral genome replication7479821
GO:0031065IMP-positive regulation of histone deacetylation21102443
GO:0035067IMP-negative regulation of histone acetylation21102443
GO:0045892ISS-negative regulation of transcription, DNA-templated-
GO:0050872ISS-white fat cell differentiation-
GO:0051726IMP-regulation of cell cycle21102443
GO:0055114IEA-oxidation-reduction process-
GO:0090241IMP-negative regulation of histone H4 acetylation21102443
GO:1903758IMP-negative regulation of transcription from RNA polymerase II promoter by histone modification21102443
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CTBP1APC10682116510875 Affinity Capture-Western
CTBP1APC10786916510875 Affinity Capture-Western
CTBP1BRCA110786910196224 Affinity Capture-Western
CTBP1BRCA110714010196224 Affinity Capture-Western
CTBP1CREBBP10777715834423 16122695 Affinity Capture-Western; Reconstituted Complex
CTBP1CREBBP10786915834423 16122695 Affinity Capture-Western; Reconstituted Complex
RBBP8CTBP11118679535825 10196224 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RBBP8CTBP11078699535825 10196224 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
HDAC1CTBP11093159650586 10995736 11022042 18765668 Affinity Capture-Western; Reconstituted Complex
HDAC1CTBP11078699650586 10995736 11022042 18765668 Affinity Capture-Western; Reconstituted Complex
KAT2BCTBP11143759824164 15834423 16122695 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
KAT2BCTBP11078699824164 15834423 16122695 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
CBX4CTBP11141059858600 11583618 12679040 12829790 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
CBX4CTBP11078699858600 11583618 12679040 12829790 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
CTBP2CTBP11078709858600 Two-hybrid
CTBP2CTBP11078699858600 Two-hybrid
ZEB1CTBP111279610359772 17967884 Affinity Capture-Western
ZEB1CTBP110786910359772 17967884 Affinity Capture-Western
IKZF1CTBP111560410766745 Affinity Capture-Western; Reconstituted Complex
IKZF1CTBP110786910766745 Affinity Capture-Western; Reconstituted Complex
HDAC2CTBP110931610766745 16036112 17967884 Affinity Capture-Western; Reconstituted Complex
HDAC2CTBP110786910766745 16036112 17967884 Affinity Capture-Western; Reconstituted Complex
TGIF1CTBP111290810995736 Affinity Capture-Western; Two-hybrid
TGIF1CTBP110786910995736 Affinity Capture-Western; Two-hybrid
HDAC5CTBP111533111022042 Reconstituted Complex
HDAC5CTBP110786911022042 Reconstituted Complex
HDAC3CTBP111436811022042 Reconstituted Complex
HDAC3CTBP110786911022042 Reconstituted Complex
HDAC9CTBP111508311022042 Reconstituted Complex
HDAC9CTBP110786911022042 Reconstituted Complex
HDAC4CTBP111510611022042 Reconstituted Complex
HDAC4CTBP110786911022042 Reconstituted Complex
MECOMCTBP110842311313276 11568182 Affinity Capture-Western; Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex
MECOMCTBP110786911313276 11568182 Affinity Capture-Western; Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex
HTTCTBP110786911739372 Affinity Capture-Western
HTTCTBP110931411739372 Affinity Capture-Western
GTF2BCTBP110921411959865 Reconstituted Complex
GTF2BCTBP110786911959865 Reconstituted Complex
TBPCTBP110786911959865 Reconstituted Complex
TBPCTBP111277111959865 Reconstituted Complex
HSD11B2CTBP110952412082639 12878208 Affinity Capture-Western
HSD11B2CTBP110786912082639 12878208 Affinity Capture-Western
IKZF4CTBP112214612444977 Affinity Capture-Western; Two-hybrid
IKZF4CTBP110786912444977 Affinity Capture-Western; Two-hybrid
LCORCTBP110786912535528 20211142 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
LCORCTBP112409312535528 20211142 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ACTL6BCTBP111952912565893 Affinity Capture-Western; Phenotypic Enhancement; Two-hybrid
ACTL6BCTBP110786912565893 Affinity Capture-Western; Phenotypic Enhancement; Two-hybrid
TCF7L2CTBP111279512711682 Reconstituted Complex
TCF7L2CTBP110786912711682 Reconstituted Complex
SIP1CTBP111405912714599 Affinity Capture-Western
SIP1CTBP110786912714599 Affinity Capture-Western
MLLCTBP111044312829790 Affinity Capture-Western; Reconstituted Complex
MLLCTBP110786912829790 Affinity Capture-Western; Reconstituted Complex
MDM2CTBP111035812867035 Affinity Capture-Western; Far Western
MDM2CTBP110786912867035 Affinity Capture-Western; Far Western
SMAD6CTBP111026614645520 Affinity Capture-Western
SMAD6CTBP110786914645520 Affinity Capture-Western
FOXP1CTBP111798914701752 Affinity Capture-Western
FOXP1CTBP110786914701752 Affinity Capture-Western
FOXP2CTBP112507314701752 Affinity Capture-Western; Two-hybrid
FOXP2CTBP110786914701752 Affinity Capture-Western; Two-hybrid
NRIP1CTBP111384315060175 18374649 Affinity Capture-Western; Reconstituted Complex
NRIP1CTBP110786915060175 18374649 Affinity Capture-Western; Reconstituted Complex
PNNCTBP111141215542832 Affinity Capture-Western; Reconstituted Complex
PNNCTBP110786915542832 Affinity Capture-Western; Reconstituted Complex
EP300CTBP110834715834423 16122695 Affinity Capture-Western; Reconstituted Complex
EP300CTBP110786915834423 16122695 Affinity Capture-Western; Reconstituted Complex
SP1CTBP111255016036112 Affinity Capture-Western
SP1CTBP110786916036112 Affinity Capture-Western
KDM1ACTBP111666716079794 16140033 17967884 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
KDM1ACTBP110786916079794 16140033 17967884 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
KAT2ACTBP110891816122695 Affinity Capture-Western
KAT2ACTBP110786916122695 Affinity Capture-Western
PLK1CTBP111136216481748 Affinity Capture-Western
PLK1CTBP110786916481748 Affinity Capture-Western
TUBG1CTBP111313416481748 Affinity Capture-Western
TUBG1CTBP110786916481748 Affinity Capture-Western
EHMT2CTBP111612316702210 17967884 Affinity Capture-Western
EHMT2CTBP110786916702210 17967884 Affinity Capture-Western
WIZCTBP112184516702210 17967884 Affinity Capture-Western
WIZCTBP110786916702210 17967884 Affinity Capture-Western
EHMT1CTBP112290816702210 Affinity Capture-Western
EHMT1CTBP110786916702210 Affinity Capture-Western
HGDCTBP110932916787403 Affinity Capture-Western
HGDCTBP110786916787403 Affinity Capture-Western
ZNF217CTBP111354717130829 17967884 18625718 19242095 Affinity Capture-MS; Affinity Capture-Western
ZNF217CTBP110786917130829 17967884 18625718 19242095 Affinity Capture-MS; Affinity Capture-Western
HIC1CTBP110933717213307 19486893 Affinity Capture-Western; Two-hybrid
HIC1CTBP110786917213307 19486893 Affinity Capture-Western; Two-hybrid
BCORL1CTBP112196117379597 Affinity Capture-Western; Co-localization
BCORL1CTBP110786917379597 Affinity Capture-Western; Co-localization
RCOR1CTBP111679617967884 19242095 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
RCOR1CTBP110786917967884 19242095 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
RREB1CTBP111215317967884 Affinity Capture-Western
RREB1CTBP110786917967884 Affinity Capture-Western
UBE2ICTBP111317717967884 Affinity Capture-Western
UBE2ICTBP110786917967884 Affinity Capture-Western
CDYLCTBP111481817967884 Affinity Capture-Western
CDYLCTBP110786917967884 Affinity Capture-Western
TBL1XCTBP110786918374649 Affinity Capture-Western
TBL1XCTBP111277018374649 Affinity Capture-Western
TP53CTBP111301018765668 Affinity Capture-Western
TP53CTBP110786918765668 Affinity Capture-Western
SATB1CTBP111221119103759 Affinity Capture-Western; Reconstituted Complex
SATB1CTBP110786919103759 Affinity Capture-Western; Reconstituted Complex
CTBP1CTBP110786919754958 Affinity Capture-Western
TCF4CTBP111278720211142 Two-hybrid
TCF4CTBP110786920211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1201685
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-010130-1'