AutismKB 2.0

Annotation Details for CTNNA1


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Basic Information Top
Gene Symbol:CTNNA1 ( CAP102,FLJ36832,FLJ52416 )
Gene Full Name: catenin (cadherin-associated protein), alpha 1, 102kDa
Band: 5q31.2
Quick LinksEntrez ID:1495; OMIM: 116805; Uniprot ID:CTNA1_HUMAN; ENSEMBL ID: ENSG00000044115; HGNC ID: 2509
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001669IEA-acrosomal vesicle-
GO:0005794IDA-Golgi apparatus-
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0005911IDA-cell-cell junction7650039
GO:0005915IEA-zonula adherens-
GO:0005925IDA-focal adhesion21423176
GO:0014704IEA-intercalated disc-
GO:0015629IEA-actin cytoskeleton-
GO:0016342IDA-catenin complex7650039
GO:0016600IEA-flotillin complex-
GO:0030027IEA-lamellipodium-
GO:0030054IDA-cell junction-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0005198IEA-structural molecule activity-
GO:0005515IPI-protein binding12477722
GO:0008013IPI-beta-catenin binding7650039
GO:0017166IPI-vinculin binding9700171
GO:0045295IPI-gamma-catenin binding7650039
GO:0045296IDA-cadherin binding25468996
GO:0045296IPI-cadherin binding7650039
GO:0046982IEA-protein heterodimerization activity-
GO:0051015IEA-actin filament binding-
GO ID Evidence Qualifier GO_term References
GO:0001541IEA-ovarian follicle development-
GO:0007015IEA-actin filament organization-
GO:0007155NAS-cell adhesion8323564
GO:0007163IEA-establishment or maintenance of cell polarity-
GO:0007406IEA-negative regulation of neuroblast proliferation-
GO:0007568IEA-aging-
GO:0008584IEA-male gonad development-
GO:0016264IEA-gap junction assembly-
GO:0031103IEA-axon regeneration-
GO:0034332TAS-adherens junction organization-
GO:0034613IEA-cellular protein localization-
GO:0042475IEA-odontogenesis of dentin-containing tooth-
GO:0043297NAS-apical junction assembly9700171
GO:0043627IEA-response to estrogen-
GO:0045880IEA-positive regulation of smoothened signaling pathway-
GO:0051149TAS-positive regulation of muscle cell differentiation-
GO:0051291IEA-protein heterooligomerization-
GO:0071681IDA-cellular response to indole-3-methanol10868478
GO:0090136IEA-epithelial cell-cell adhesion-
GO:2000146IEA-negative regulation of cell motility-
GO:2001045IEA-negative regulation of integrin-mediated signaling pathway-
GO:2001240IEA-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-
GO:2001241IEA-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CTNNA1ACTN11078767790378 Affinity Capture-Western
CTNNA1ACTN11066027790378 Affinity Capture-Western
CTNNA1APC1068217651399 8259519 20936779 Affinity Capture-Western; Two-hybrid
CTNNA1APC1078767651399 8259519 20936779 Affinity Capture-Western; Two-hybrid
CTNNA1CA910722314567991 Affinity Capture-Western
CTNNA1CA910787614567991 Affinity Capture-Western
CTNNA1CDH11078767542250 8227214 9233779 10381631 11960376 Affinity Capture-Western
CTNNA1CDH11074347542250 8227214 9233779 10381631 11960376 Affinity Capture-Western
CTNNA1CDH210743512604612 14625392 Affinity Capture-MS; Affinity Capture-Western
CTNNA1CDH210787612604612 14625392 Affinity Capture-MS; Affinity Capture-Western
CTNNA1CDH310743610381631 10910767 Affinity Capture-Western; Co-purification
CTNNA1CDH310787610381631 10910767 Affinity Capture-Western; Co-purification
CTNNA1CDH51074389434630 12003790 Affinity Capture-Western
CTNNA1CDH51078769434630 12003790 Affinity Capture-Western
JUPCTNNA11099317650039 9110993 9762469 20936779 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
JUPCTNNA11078767650039 9110993 9762469 20936779 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CTNND1CTNNA11078767651399 Affinity Capture-Western
CTNND1CTNNA11078817651399 Affinity Capture-Western
CTNNB1CTNNA11078767706414 7954478 9512503 9762469 12640114 Affinity Capture-Western; Reconstituted Complex
CTNNB1CTNNA11078807706414 7954478 9512503 9762469 12640114 Affinity Capture-Western; Reconstituted Complex
DLG1CTNNA11078769512503 Affinity Capture-Western
DLG1CTNNA11080839512503 Affinity Capture-Western
VCLCTNNA11078769700171 Reconstituted Complex
VCLCTNNA11132579700171 Reconstituted Complex
CTNNA1CTNNA11078769762469 Affinity Capture-Western
TJP2CTNNA111480910026224 Reconstituted Complex
TJP2CTNNA110787610026224 Reconstituted Complex
PSEN1CTNNA110787610635315 Affinity Capture-Western
PSEN1CTNNA111164210635315 Affinity Capture-Western
SPTBN1CTNNA110787611069925 Reconstituted Complex
SPTBN1CTNNA111258911069925 Reconstituted Complex
MYO7ACTNNA111073111080149 Affinity Capture-Western
MYO7ACTNNA110787611080149 Affinity Capture-Western
VEZTCTNNA110787611080149 Affinity Capture-Western
VEZTCTNNA112073611080149 Affinity Capture-Western
MLLT4CTNNA111044711907041 Reconstituted Complex
MLLT4CTNNA110787611907041 Reconstituted Complex
FAM84BCTNNA112760912477722 Two-hybrid
FAM84BCTNNA110787612477722 Two-hybrid
PTPN14CTNNA111174812808048 Affinity Capture-MS
PTPN14CTNNA110787612808048 Affinity Capture-MS
RNF219CTNNA112273620936779 Two-hybrid
RNF219CTNNA110787620936779 Two-hybrid
ZGPATCTNNA112415020936779 Two-hybrid
ZGPATCTNNA110787620936779 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
CTNNA1rs700626, rs891996 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:88274
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-991207-24'