AutismKB 2.0

Annotation Details for SIK1


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Basic Information Top
Gene Symbol:SIK1 ( MSK,SIK,SNF1LK )
Gene Full Name: salt-inducible kinase 1
Band: 21q22.3
Quick LinksEntrez ID:150094; OMIM: 605705; Uniprot ID:SIK1_HUMAN; ENSEMBL ID: ENSG00000142178; HGNC ID: 11142
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus16306228
GO:0005737IDA-cytoplasm16306228
GO:0005737ISS-cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0000287IDA-magnesium ion binding14976552
GO:0000287ISS-magnesium ion binding-
GO:0004674IDA-protein serine/threonine kinase activity14976552
GO:0005515IPI-protein binding16306228
GO:0005524IDA-ATP binding14976552
GO:0005524ISS-ATP binding-
GO:0008140ISS-cAMP response element binding protein binding-
GO:0019901IPI-protein kinase binding18348280
GO:0071889IDA-14-3-3 protein binding18348280
GO ID Evidence Qualifier GO_term References
GO:0002028ISS-regulation of sodium ion transport-
GO:0006468IDA-protein phosphorylation14976552
GO:0006468ISS-protein phosphorylation-
GO:0007049IEA-cell cycle-
GO:0007346ISS-regulation of mitotic cell cycle-
GO:0010830ISS-regulation of myotube differentiation-
GO:0010868ISS-negative regulation of triglyceride biosynthetic process-
GO:0032792ISS-negative regulation of CREB transcription factor activity-
GO:0032870IBA-cellular response to hormone stimulus-
GO:0035556IDA-intracellular signal transduction14976552
GO:0035556ISS-intracellular signal transduction-
GO:0043153ISS-entrainment of circadian clock by photoperiod-
GO:0045595ISS-regulation of cell differentiation-
GO:0045721ISS-negative regulation of gluconeogenesis-
GO:0046777IDA-protein autophosphorylation18348280
GO:0048511IEA-rhythmic process-
GO:0055007ISS-cardiac muscle cell differentiation-
GO:2000210IMP-positive regulation of anoikis19622832
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104754
  • Data Attributes: MGI curated and HomoloGene calculated
No data