AutismKB 2.0

Annotation Details for CTSB


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Basic Information Top
Gene Symbol:CTSB ( APPS,CPSB )
Gene Full Name: cathepsin B
Band: 8p23.1
Quick LinksEntrez ID:1508; OMIM: 116810; Uniprot ID:CATB_HUMAN; ENSEMBL ID: ENSG00000164733; HGNC ID: 2527
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space22952693
GO:0005615ISS-extracellular space22261194
GO:0005622TAS-intracellular1645961
GO:0005730IDA-nucleolus-
GO:0005739IEA-mitochondrion-
GO:0005764IDA-lysosome1837142
GO:0036021TAS-endolysosome lumen-
GO:0042470IEA-melanosome-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0048471IDA-perinuclear region of cytoplasm15614436
GO:0070062IDA-extracellular exosome19199708
GO:1904813TAS-ficolin-1-rich granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0004197IDA-cysteine-type endopeptidase activity6203523
GO:0004252TAS-serine-type endopeptidase activity-
GO:0005515IPI-protein binding6203523
GO:0005518IDA-collagen binding22952693
GO:0008233IDA-peptidase activity7890620
GO:0008234IDA-cysteine-type peptidase activity8612130
GO:0043394IPI-proteoglycan binding22952693
GO ID Evidence Qualifier GO_term References
GO:0002224TAS-toll-like receptor signaling pathway-
GO:0006508IDA-proteolysis7890620
GO:0030574IDA-collagen catabolic process22952693
GO:0030574TAS-collagen catabolic process-
GO:0030855IEP-epithelial cell differentiation21492153
GO:0042981TAS-regulation of apoptotic process16130169
GO:0043312TAS-neutrophil degranulation-
GO:0046697IEA-decidualization-
GO:0046718IEA-viral entry into host cell-
GO:0050790IEA-regulation of catalytic activity-
GO:0051603IDA-proteolysis involved in cellular protein catabolic process22952693
GO:0097067IEP-cellular response to thyroid hormone stimulus21217776
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CTSBANXA210788810777578 Reconstituted Complex
CTSBANXA210679910777578 Reconstituted Complex
CTSBCST310788814503883 Reconstituted Complex
CTSBCST310785314503883 Reconstituted Complex
CTSBCSTA1078889585570 14503883 Reconstituted Complex
CTSBCSTA1078579585570 14503883 Reconstituted Complex
CTSBCSTB10785811514663 14503883 Reconstituted Complex
CTSBCSTB10788811514663 14503883 Reconstituted Complex
S100A10CTSB11218910777578 Reconstituted Complex; Two-hybrid
S100A10CTSB10788810777578 Reconstituted Complex; Two-hybrid
UBQLN4CTSB10788811162551 Two-hybrid
UBQLN4CTSB12122311162551 Two-hybrid
BAT3CTSB10788816169070 Two-hybrid
BAT3CTSB11364716169070 Two-hybrid
DMWDCTSB10810219615732 Affinity Capture-MS
DMWDCTSB10788819615732 Affinity Capture-MS
USP29CTSB10788819615732 Affinity Capture-MS
USP29CTSB12169619615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
CTSBrs12338, rs1293303, rs8898 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:88561
  • Data Attributes: MGI curated and HomoloGene calculated
No data