AutismKB 2.0

Annotation Details for CTSD


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Basic Information Top
Gene Symbol:CTSD ( CLN10,CPSD,MGC2311 )
Gene Full Name: cathepsin D
Band: 11p15.5
Quick LinksEntrez ID:1509; OMIM: 116840; Uniprot ID:CATD_HUMAN; ENSEMBL ID: ENSG00000117984; HGNC ID: 2529
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576NAS-extracellular region14718574
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space16502470
GO:0005615ISS-extracellular space22261194
GO:0005764IDA-lysosome1837142
GO:0031012IDAcolocalizes_withextracellular matrix20551380
GO:0035580TAS-specific granule lumen-
GO:0042470IEA-melanosome-
GO:0043202TAS-lysosomal lumen-
GO:0045121IDA-membrane raft25204797
GO:0070062IDA-extracellular exosome19056867
GO:1904724TAS-tertiary granule lumen-
GO:1904813TAS-ficolin-1-rich granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0004190IBA-aspartic-type endopeptidase activity-
GO:0004197TAS-cysteine-type endopeptidase activity-
GO:0004252TAS-serine-type endopeptidase activity-
GO:0005515IPI-protein binding17112520
GO ID Evidence Qualifier GO_term References
GO:0006508IBA-proteolysis-
GO:0006914IBA-autophagy-
GO:0019886TAS-antigen processing and presentation of exogenous peptide antigen via MHC class II-
GO:0030163IBA-protein catabolic process-
GO:0030574TAS-collagen catabolic process-
GO:0043312TAS-neutrophil degranulation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PSAPCTSD10788912083803 Affinity Capture-Western
PSAPCTSD11163912083803 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
CTSDrs17571, rs17834326, rs2292962, rs2292963 Gene overview in AlzGene
Gene Symbol Poly Names Gene overview in PDGene
CTSDrs17571 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:88562
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-010131-8'