AutismKB 2.0

Annotation Details for CTSG


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Basic Information Top
Gene Symbol:CTSG ( CG,MGC23078 )
Gene Full Name: cathepsin G
Band: 14q12
Quick LinksEntrez ID:1511; OMIM: 116830; Uniprot ID:CATG_HUMAN; ENSEMBL ID: ENSG00000100448; HGNC ID: 2532
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space20551380
GO:0005634IDA-nucleus21630459
GO:0005886IDA-plasma membrane1861080
GO:0005886TAS-plasma membrane-
GO:0009986IEA-cell surface-
GO:0010494IDA-cytoplasmic stress granule1937776
GO:0030141IDA-secretory granule11907569
GO:0031012IDAcolocalizes_withextracellular matrix20551380
GO:0035578TAS-azurophil granule lumen-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0004252EXP-serine-type endopeptidase activity10512690
GO:0004252IDA-serine-type endopeptidase activity8194606
GO:0004252TAS-serine-type endopeptidase activity-
GO:0005515IPI-protein binding25416956
GO:0008201IDA-heparin binding11907569
GO:0008233IDA-peptidase activity11907569
GO:0008236IMP-serine-type peptidase activity1937776
GO ID Evidence Qualifier GO_term References
GO:0002003TAS-angiotensin maturation-
GO:0006468IDA-protein phosphorylation8573071
GO:0006508IDA-proteolysis1861080
GO:0006955TAS-immune response2569462
GO:0016485IBA-protein processing-
GO:0019730TAS-antimicrobial humoral response-
GO:0019731IDA-antibacterial humoral response1937776
GO:0022617TAS-extracellular matrix disassembly-
GO:0043312TAS-neutrophil degranulation-
GO:0044130IEA-negative regulation of growth of symbiont in host-
GO:0044267TAS-cellular protein metabolic process-
GO:0050778IEA-positive regulation of immune response-
GO:0050829IDA-defense response to Gram-negative bacterium1937776
GO:0050832IEA-defense response to fungus-
GO:0070946IEA-neutrophil mediated killing of gram-positive bacterium-
GO:0071222IDA-cellular response to lipopolysaccharide1937776
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SDC1CTSG1078919565572 Reconstituted Complex
SDC1CTSG1122849565572 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
CTSGCTSG-exon 4 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:88563
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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