AutismKB 2.0

Annotation Details for PYDC2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PYDC2 ( POP2,cPOP2 )
Gene Full Name: pyrin domain containing 2
Band: 3q28
Quick LinksEntrez ID:152138; OMIM: NA; Uniprot ID:PYDC2_HUMAN; ENSEMBL ID: ; HGNC ID: 33512
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus17178784
GO:0005737IDA-cytoplasm17178784
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding17178784
GO ID Evidence Qualifier GO_term References
GO:0006954IEA-inflammatory response-
GO:0010804IMP-negative regulation of tumor necrosis factor-mediated signaling pathway17339483
GO:0032088IMP-negative regulation of NF-kappaB transcription factor activity17339483
GO:0042347IMP-negative regulation of NF-kappaB import into nucleus17339483
GO:0045087IEA-innate immune response-
GO:0050713IMP-negative regulation of interleukin-1 beta secretion17178784
GO:0050728IMP-negative regulation of inflammatory response17178784
GO:1900226IMP-negative regulation of NLRP3 inflammasome complex assembly17339483
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018