AutismKB 2.0

Annotation Details for CTSZ


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Basic Information Top
Gene Symbol:CTSZ ( CTSX,FLJ17088 )
Gene Full Name: cathepsin Z
Band: 20q13.32
Quick LinksEntrez ID:1522; OMIM: 603169; Uniprot ID:CATZ_HUMAN; ENSEMBL ID: ENSG00000101160; HGNC ID: 2547
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000139IEA-Golgi membrane-
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space19433310
GO:0005764IBA-lysosome-
GO:0005764IDA-lysosome19433310
GO:0005783IDA-endoplasmic reticulum-
GO:0005788TAS-endoplasmic reticulum lumen-
GO:0005886TAS-plasma membrane-
GO:0009986IEA-cell surface-
GO:0030134TAS-ER to Golgi transport vesicle-
GO:0030426IEA-growth cone-
GO:0031410IDA-cytoplasmic vesicle19433310
GO:0033116TAS-endoplasmic reticulum-Golgi intermediate compartment membrane-
GO:0035580TAS-specific granule lumen-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0070062IDA-extracellular exosome23376485
GO:0099738IDA-cell cortex region19433310
GO:1904813TAS-ficolin-1-rich granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0004180IMP-carboxypeptidase activity19433310
GO:0004197IBA-cysteine-type endopeptidase activity-
GO:0005515IPI-protein binding21516116
GO:0008234TAS-cysteine-type peptidase activity-
GO ID Evidence Qualifier GO_term References
GO:0002003TAS-angiotensin maturation-
GO:0006508IMP-proteolysis19433310
GO:0006888TAS-ER to Golgi vesicle-mediated transport-
GO:0010757IMP-negative regulation of plasminogen activation19433310
GO:0010977IEA-negative regulation of neuron projection development-
GO:0032091IDA-negative regulation of protein binding19433310
GO:0043312TAS-neutrophil degranulation-
GO:0043525IEA-positive regulation of neuron apoptotic process-
GO:0048208TAS-COPII vesicle coating-
GO:0051603IBA-proteolysis involved in cellular protein catabolic process-
GO:0060441IEA-epithelial tube branching involved in lung morphogenesis-
GO:1901214IGI-regulation of neuron death19433310
GO:2000179IEA-positive regulation of neural precursor cell proliferation-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1891190
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041010-139'