AutismKB 2.0

Annotation Details for CYBB


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Basic Information Top
Gene Symbol:CYBB ( CGD,GP91-1,GP91-PHOX,GP91PHOX,NOX2,p91-PHOX )
Gene Full Name: cytochrome b-245, beta polypeptide
Band: Xp21.1-p11.4
Quick LinksEntrez ID:1536; OMIM: 300481; Uniprot ID:CY24B_HUMAN; ENSEMBL ID: ENSG00000165168; HGNC ID: 2578
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005635IEA-nuclear envelope-
GO:0005739IEA-mitochondrion-
GO:0005789TAS-endoplasmic reticulum membrane-
GO:0005791IEA-rough endoplasmic reticulum-
GO:0005794IEA-Golgi apparatus-
GO:0005886TAS-plasma membrane-
GO:0005887IDA-integral component of plasma membrane15233623
GO:0030425IEA-dendrite-
GO:0030670TAS-phagocytic vesicle membrane-
GO:0035579TAS-specific granule membrane-
GO:0043020IDA-NADPH oxidase complex3305576
GO:0043020TAS-NADPH oxidase complex12716910
GO:0043025IEA-neuronal cell body-
GO:0048471IEA-perinuclear region of cytoplasm-
GO:0070821TAS-tertiary granule membrane-
GO ID Evidence Qualifier GO_term References
GO:0005244IEA-voltage-gated ion channel activity-
GO:0005515IPI-protein binding3305576
GO:0009055IDAcontributes_toelectron carrier activity12042318
GO:0016175IDAcontributes_tosuperoxide-generating NADPH oxidase activity12042318
GO:0016175TAS-superoxide-generating NADPH oxidase activity12716910
GO:0020037IMP-heme binding9774399
GO:0046872IEA-metal ion binding-
GO:0046982IPI-protein heterodimerization activity12042318
GO:0050660IMP-flavin adenine dinucleotide binding9774399
GO ID Evidence Qualifier GO_term References
GO:0002479TAS-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-
GO:0006801IDA-superoxide metabolic process12042318
GO:0006801TAS-superoxide metabolic process12716910
GO:0006811IEA-ion transport-
GO:0006954ISS-inflammatory response-
GO:0007584IEA-response to nutrient-
GO:0034599TAS-cellular response to oxidative stress-
GO:0034765IEA-regulation of ion transmembrane transport-
GO:0042493IEA-response to drug-
GO:0042535IEA-positive regulation of tumor necrosis factor biosynthetic process-
GO:0042554IDA-superoxide anion generation12042318
GO:0042554TAS-superoxide anion generation12716910
GO:0043312TAS-neutrophil degranulation-
GO:0045087IMP-innate immune response9774399
GO:0045087TAS-innate immune response12716910
GO:0045454TAS-cell redox homeostasis-
GO:0045730IMP-respiratory burst9774399
GO:0045730TAS-respiratory burst12716910
GO:0045766IEA-positive regulation of angiogenesis-
GO:0048010TAS-vascular endothelial growth factor receptor signaling pathway-
GO:0050665IEA-hydrogen peroxide biosynthetic process-
GO:0055114IDA-oxidation-reduction process12042318
GO:0055114TAS-oxidation-reduction process12716910
GO:0071276IEA-cellular response to cadmium ion-
GO:0071361IEA-cellular response to ethanol-
GO:0097411IEA-hypoxia-inducible factor-1alpha signaling pathway-
GO:1904044IEA-response to aldosterone-
GO:1904845IEA-cellular response to L-glutamine-
GO:1990776IEA-response to angiotensin-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88574
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1380'