AutismKB 2.0

Annotation Details for CYP1B1


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Basic Information Top
Gene Symbol:CYP1B1 ( CP1B,GLC3A,P4501B1 )
Gene Full Name: cytochrome P450, family 1, subfamily B, polypeptide 1
Band: 2p22.2
Quick LinksEntrez ID:1545; OMIM: 601771; Uniprot ID:CP1B1_HUMAN; ENSEMBL ID: ENSG00000138061; HGNC ID: 2597
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739ISS-mitochondrion-
GO:0005789TAS-endoplasmic reticulum membrane-
GO:0031090IEA-organelle membrane-
GO:0043231IBA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0004497IDA-monooxygenase activity15258110
GO:0004497TAS-monooxygenase activity9097971
GO:0005506IEA-iron ion binding-
GO:0016712IDA-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen10871058
GO:0019825TAS-oxygen binding9097971
GO:0020037IDA-heme binding21147782
GO:0020037TAS-heme binding9097971
GO:0070330IEA-aromatase activity-
GO ID Evidence Qualifier GO_term References
GO:0001525IEA-angiogenesis-
GO:0002930ISS-trabecular meshwork development-
GO:0006725IEA-cellular aromatic compound metabolic process-
GO:0006805IDA-xenobiotic metabolic process22888116
GO:0006809ISS-nitric oxide biosynthetic process-
GO:0007155ISS-cell adhesion-
GO:0007601TAS-visual perception9097971
GO:0008202IDA-steroid metabolic process22888116
GO:0008210IDA-estrogen metabolic process23821647
GO:0008285ISS-negative regulation of cell proliferation-
GO:0008631ISS-intrinsic apoptotic signaling pathway in response to oxidative stress-
GO:0009404IEA-toxin metabolic process-
GO:0009636IEA-response to toxic substance-
GO:0010575ISS-positive regulation of vascular endothelial growth factor production-
GO:0016125TAS-sterol metabolic process-
GO:0019369IDA-arachidonic acid metabolic process15258110
GO:0019373TAS-epoxygenase P450 pathway-
GO:0030199ISS-collagen fibril organization-
GO:0030336ISS-negative regulation of cell migration-
GO:0032088ISS-negative regulation of NF-kappaB transcription factor activity-
GO:0033629ISS-negative regulation of cell adhesion mediated by integrin-
GO:0042572IDA-retinol metabolic process15258110
GO:0042574IDA-retinal metabolic process15258110
GO:0043065ISS-positive regulation of apoptotic process-
GO:0043542ISS-endothelial cell migration-
GO:0045766ISS-positive regulation of angiogenesis-
GO:0046427ISS-positive regulation of JAK-STAT cascade-
GO:0046466ISS-membrane lipid catabolic process-
GO:0048514ISS-blood vessel morphogenesis-
GO:0055114TAS-oxidation-reduction process9097971
GO:0061304ISS-retinal blood vessel morphogenesis-
GO:0070301ISS-cellular response to hydrogen peroxide-
GO:0071407IDA-cellular response to organic cyclic compound23275542
GO:0071603IEA-endothelial cell-cell adhesion-
GO:0097267TAS-omega-hydroxylase P450 pathway-
GO:2000377ISS-regulation of reactive oxygen species metabolic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SAE1CYP1B110792517353931 Affinity Capture-MS
SAE1CYP1B111536617353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
CYP1B1rs1056836 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:88590
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030902-1'