AutismKB 2.0

Annotation Details for ADRB3


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Basic Information Top
Gene Symbol:ADRB3 ( BETA3AR,FLJ99960 )
Gene Full Name: adrenergic, beta-3-, receptor
Band: 8p11.23
Quick LinksEntrez ID:155; OMIM: 109691; Uniprot ID:ADRB3_HUMAN; ENSEMBL ID: ENSG00000188778; HGNC ID: 288
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane1718744
GO:0043235IDA-receptor complex15123695
GO ID Evidence Qualifier GO_term References
GO:0004939IDA-beta-adrenergic receptor activity15123695
GO:0005515IPI-protein binding15123695
GO:0015052IMP-beta3-adrenergic receptor activity9892244
GO:0031699IEA-beta-3 adrenergic receptor binding-
GO:0042803IDA-protein homodimerization activity15123695
GO:0051379IBA-epinephrine binding-
GO:0051380IDAcontributes_tonorepinephrine binding15123695
GO ID Evidence Qualifier GO_term References
GO:0001659IBA-temperature homeostasis-
GO:0002024IEA-diet induced thermogenesis-
GO:0002025IBA-norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure-
GO:0002032IDANOTdesensitization of G-protein coupled receptor protein signaling pathway by arrestin15123695
GO:0005975TAS-carbohydrate metabolic process2570461
GO:0006091TAS-generation of precursor metabolites and energy2570461
GO:0006112TAS-energy reserve metabolic process1718744
GO:0006898IDANOTreceptor-mediated endocytosis15123695
GO:0007187TAS-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger2570461
GO:0007188TAS-adenylate cyclase-modulating G-protein coupled receptor signaling pathway1718744
GO:0007190IDA-activation of adenylate cyclase activity15123695
GO:0007267IBA-cell-cell signaling-
GO:0007568IEA-aging-
GO:0009409IEA-response to cold-
GO:0031649IEA-heat generation-
GO:0040015IEA-negative regulation of multicellular organism growth-
GO:0042755IEA-eating behavior-
GO:0043410IDA-positive regulation of MAPK cascade15123695
GO:0046677IEA-response to antibiotic-
GO:0050873IEA-brown fat cell differentiation-
GO:0071880IBA-adenylate cyclase-activating adrenergic receptor signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SRCADRB311259211013230 Affinity Capture-Western; Reconstituted Complex
SRCADRB310666411013230 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
ADRB3rs4998 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:87939
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-080917-21'