Annotation Details for CYP2C8

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Basic Information Top

Gene Symbol:	CYP2C8 ( CPC8,MP-12/MP-20 )
Gene Full Name:	cytochrome P450, family 2, subfamily C, polypeptide 8
Band:	10q23.33
Quick Links	Entrez ID:1558; OMIM: 601129; Uniprot ID:CP2C8_HUMAN; ENSEMBL ID: ENSG00000138115; HGNC ID: 2622
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:2 results
Molecular Function:9 results
Biological Process:11 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005789	TAS	-	endoplasmic reticulum membrane	-
GO:0031090	IEA	-	organelle membrane	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0004497	IDA	-	monooxygenase activity	19651758
GO:0004497	TAS	-	monooxygenase activity	-
GO:0005506	IEA	-	iron ion binding	-
GO:0008392	IBA	-	arachidonic acid epoxygenase activity	-
GO:0019825	TAS	-	oxygen binding	-
GO:0020037	IEA	-	heme binding	-
GO:0034875	IDA	-	caffeine oxidase activity	18619574
GO:0070330	IEA	-	aromatase activity	-
GO:0101020	IDA	-	estrogen 16-alpha-hydroxylase activity	14559847

GO ID	Evidence	Qualifier	GO_term	References
GO:0002933	IDA	-	lipid hydroxylation	14559847
GO:0006082	IDA	-	organic acid metabolic process	19651758
GO:0006805	TAS	-	xenobiotic metabolic process	-
GO:0008202	IDA	-	steroid metabolic process	14559847
GO:0017144	IDA	-	drug metabolic process	19651758
GO:0019373	IBA	-	epoxygenase P450 pathway	-
GO:0019373	TAS	-	epoxygenase P450 pathway	-
GO:0042738	IDA	-	exogenous drug catabolic process	18619574
GO:0055114	IDA	-	oxidation-reduction process	19651758
GO:0070989	IDA	-	oxidative demethylation	18619574
GO:0097267	TAS	-	omega-hydroxylase P450 pathway	-

Protein-Protein Interaction

AlzGene, PDGene and SZGene

Alz Gene:1 results
PD Gene:0 results
SZ Gene:0 results

Gene Symbol	Poly Names	Gene overview in AlzGene
CYP2C8	rs1058932	Gene overview in AlzGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:1917138
Data Attributes: HomoloGene calculated

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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