AutismKB 2.0

Annotation Details for CYP2E1


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Basic Information Top
Gene Symbol:CYP2E1 ( CPE1,CYP2E,P450-J,P450C2E )
Gene Full Name: cytochrome P450, family 2, subfamily E, polypeptide 1
Band: 10q26.3
Quick LinksEntrez ID:1571; OMIM: 124040; Uniprot ID:CP2E1_HUMAN; ENSEMBL ID: ENSG00000130649; HGNC ID: 2631
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000139IEA-Golgi membrane-
GO:0005739IEA-mitochondrion-
GO:0005789TAS-endoplasmic reticulum membrane-
GO:0031227IEA-intrinsic component of endoplasmic reticulum membrane-
GO ID Evidence Qualifier GO_term References
GO:0004497IDA-monooxygenase activity19651758
GO:0005506IEA-iron ion binding-
GO:0008392IBA-arachidonic acid epoxygenase activity-
GO:0016491IDA-oxidoreductase activity16401082
GO:0016709TAS-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen18818195
GO:0016712IEA-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen-
GO:0019825TAS-oxygen binding-
GO:0019899IPI-enzyme binding15680923
GO:0020037IDA-heme binding18818195
GO ID Evidence Qualifier GO_term References
GO:0006641IEA-triglyceride metabolic process-
GO:0006805TAS-xenobiotic metabolic process-
GO:0008202IMP-steroid metabolic process18356043
GO:0010193IEA-response to ozone-
GO:0010243IEA-response to organonitrogen compound-
GO:0016098IDA-monoterpenoid metabolic process16401082
GO:0017144IDA-drug metabolic process19219744
GO:0017144IMP-drug metabolic process18356043
GO:0017144TAS-drug metabolic process-
GO:0018885TAS-carbon tetrachloride metabolic process-
GO:0018910TAS-benzene metabolic process-
GO:0019373IBA-epoxygenase P450 pathway-
GO:0042197TAS-halogenated hydrocarbon metabolic process-
GO:0042493IEA-response to drug-
GO:0045471IEA-response to ethanol-
GO:0046483IDA-heterocycle metabolic process19651758
GO:0055114IDA-oxidation-reduction process16401082
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PORCYP2E11079449398194 Reconstituted Complex
PORCYP2E11114439398194 Reconstituted Complex
FANCGCYP2E110794414499622 Two-hybrid
FANCGCYP2E110848414499622 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
CYP2E1CYP2E1_Dral, rs2031920, rs2070676, rs2249695, rs743534, rs915906, rs915907, rs915908 Gene overview in PDGene
Gene Symbol Poly Names Gene overview in SZGene
CYP2E1CYP2E1_C1/C2 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:88607
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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