Annotation Details for CYP27B1
Basic Information Top
| Gene Symbol: | CYP27B1 ( CP2B,CYP1,CYP1alpha,CYP27B,P450c1,PDDR,VDD1,VDDR,VDDRI,VDR ) |
|---|---|
| Gene Full Name: | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| Band: | 12q14.1 |
| Quick Links | Entrez ID:1594; OMIM: 609506; Uniprot ID:CP27B_HUMAN; ENSEMBL ID: ENSG00000111012; HGNC ID: 2606 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005737 | IDA | - | cytoplasm | 15589699 |
| GO:0005739 | ISS | - | mitochondrion | - |
| GO:0005739 | TAS | - | mitochondrion | 9333115 |
| GO:0005741 | TAS | - | mitochondrial outer membrane | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0004498 | IDA | - | calcidiol 1-monooxygenase activity | 9415400 |
| GO:0004498 | TAS | - | calcidiol 1-monooxygenase activity | - |
| GO:0005506 | IEA | - | iron ion binding | - |
| GO:0020037 | IEA | - | heme binding | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0006766 | TAS | - | vitamin metabolic process | - |
| GO:0006816 | ISS | - | calcium ion transport | - |
| GO:0008285 | IDA | - | negative regulation of cell proliferation | 16549446 |
| GO:0010956 | IDA | - | negative regulation of calcidiol 1-monooxygenase activity | 16549446 |
| GO:0010980 | IDA | - | positive regulation of vitamin D 24-hydroxylase activity | 16549446 |
| GO:0030282 | IEP | - | bone mineralization | 17023519 |
| GO:0030308 | IMP | - | negative regulation of cell growth | 12496369 |
| GO:0030500 | IMP | - | regulation of bone mineralization | 9415400 |
| GO:0032496 | IDA | - | response to lipopolysaccharide | 12855575 |
| GO:0033280 | IDA | - | response to vitamin D | 16549446 |
| GO:0034341 | IDA | - | response to interferon-gamma | 9282826 |
| GO:0036378 | IDA | - | calcitriol biosynthetic process from calciol | 9415400 |
| GO:0042359 | IDA | - | vitamin D metabolic process | 9415400 |
| GO:0042359 | TAS | - | vitamin D metabolic process | - |
| GO:0042369 | IEA | - | vitamin D catabolic process | - |
| GO:0043627 | IEP | - | response to estrogen | 15795327 |
| GO:0045618 | IMP | - | positive regulation of keratinocyte differentiation | 12496369 |
| GO:0046697 | IEP | - | decidualization | 16720713 |
| GO:0055074 | IMP | - | calcium ion homeostasis | 9415400 |
| GO:0055114 | IEA | - | oxidation-reduction process | - |
| GO:0070314 | IMP | - | G1 to G0 transition | 12496369 |
| GO:0070564 | IDA | - | positive regulation of vitamin D receptor signaling pathway | 16549446 |
Protein-Protein Interaction