AutismKB 2.0

Annotation Details for DAB1


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Basic Information Top
Gene Symbol:DAB1 ( - )
Gene Full Name: disabled homolog 1 (Drosophila)
Band: 1p32.2
Quick LinksEntrez ID:1600; OMIM: 603448; Uniprot ID:DAB1_HUMAN; ENSEMBL ID: ENSG00000173406; HGNC ID: 2661
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0005903IEA-brush border-
GO:0014069IEA-postsynaptic density-
GO:0016020IEA-membrane-
GO:0043005IEA-neuron projection-
GO:0043025IEA-neuronal cell body-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0045177IEA-apical part of cell-
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding25416956
GO:0043548IEA-phosphatidylinositol 3-kinase binding-
GO ID Evidence Qualifier GO_term References
GO:0007162IEA-negative regulation of cell adhesion-
GO:0007264IEA-small GTPase mediated signal transduction-
GO:0007411TAS-axon guidance-
GO:0007494IEA-midgut development-
GO:0007628IEA-adult walking behavior-
GO:0016358IEA-dendrite development-
GO:0021517IEA-ventral spinal cord development-
GO:0021589IEA-cerebellum structural organization-
GO:0021813IEA-cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration-
GO:0021942IEA-radial glia guided migration of Purkinje cell-
GO:0042493IEA-response to drug-
GO:0045666IEA-positive regulation of neuron differentiation-
GO:0045860IEA-positive regulation of protein kinase activity-
GO:0046426IEA-negative regulation of JAK-STAT cascade-
GO:0048712IEA-negative regulation of astrocyte differentiation-
GO:0050771IEA-negative regulation of axonogenesis-
GO:0051645IEA-Golgi localization-
GO:0097477IEA-lateral motor column neuron migration-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DAB1APLP110797010460257 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
DAB1APLP110683010460257 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
DAB1APLP210797010460257 Reconstituted Complex
DAB1APLP210683110460257 Reconstituted Complex
DAB1APP10797010460257 Reconstituted Complex
DAB1APP10684810460257 Reconstituted Complex
LDLRDAB11079709837937 10827173 Reconstituted Complex; Two-hybrid
LDLRDAB11101419837937 10827173 Reconstituted Complex; Two-hybrid
LRP1DAB11102159837937 10827173 Reconstituted Complex; Two-hybrid
LRP1DAB11079709837937 10827173 Reconstituted Complex; Two-hybrid
LRP2DAB111021610827173 12508107 Reconstituted Complex; Two-hybrid
LRP2DAB110797010827173 12508107 Reconstituted Complex; Two-hybrid
VLDLRDAB111327710827173 Two-hybrid
VLDLRDAB110797010827173 Two-hybrid
LRP8DAB111357910827173 Two-hybrid
LRP8DAB110797010827173 Two-hybrid
MYO6DAB111073011967127 Reconstituted Complex
MYO6DAB110797011967127 Reconstituted Complex
SIAH1DAB111237212646221 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SIAH1DAB110797012646221 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
DAB1rs1188008, rs1202822, rs12120223, rs1213757, rs1341743, rs1416343, rs1503646, rs1504589, rs1556585, rs338901, rs4110981, rs514412, rs632935, rs7528953, rs852778, rs985783 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:108554
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060421-7958'