AutismKB 2.0

Annotation Details for DAPK3


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Basic Information Top
Gene Symbol:DAPK3 ( FLJ36473,ZIP,ZIPK )
Gene Full Name: death-associated protein kinase 3
Band: 19p13.3
Quick LinksEntrez ID:1613; OMIM: 603289; Uniprot ID:DAPK3_HUMAN; ENSEMBL ID: ENSG00000167657; HGNC ID: 2676
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005634IDA-nucleus-
GO:0005634ISS-nucleus-
GO:0005737IBA-cytoplasm-
GO:0005884IEA-actin filament-
GO:0016605IEA-PML body-
GO:0045121IEA-membrane raft-
GO ID Evidence Qualifier GO_term References
GO:0004674IDA-protein serine/threonine kinase activity10356987
GO:0004674TAS-protein serine/threonine kinase activity16756490
GO:0005515IPI-protein binding15292222
GO:0005524IDA-ATP binding10356987
GO:0008022IEA-protein C-terminus binding-
GO:0008140TAS-cAMP response element binding protein binding14685163
GO:0017048IDA-Rho GTPase binding23454120
GO:0042802IPI-identical protein binding18239682
GO:0042803IDA-protein homodimerization activity18239682
GO:0043522IPI-leucine zipper domain binding10580117
GO ID Evidence Qualifier GO_term References
GO:0000910TAS-cytokinesis-
GO:0006351IEA-transcription, DNA-templated-
GO:0006355TAS-regulation of transcription, DNA-templated-
GO:0006468IDA-protein phosphorylation10356987
GO:0006915IDA-apoptotic process10580117
GO:0006915IMP-apoptotic process12917339
GO:0006940TAS-regulation of smooth muscle contraction-
GO:0007088TAS-regulation of mitotic nuclear division-
GO:0007346IMP-regulation of mitotic cell cycle21487036
GO:0008360IEA-regulation of cell shape-
GO:0010506TAS-regulation of autophagy16756490
GO:0016569IEA-covalent chromatin modification-
GO:0017148IDA-negative regulation of translation18995835
GO:0018105IBA-peptidyl-serine phosphorylation-
GO:0018107IBA-peptidyl-threonine phosphorylation-
GO:0030182IEA-neuron differentiation-
GO:0030335IEA-positive regulation of cell migration-
GO:0035556IDA-intracellular signal transduction10356987
GO:0042981TAS-regulation of apoptotic process16756490
GO:0043065IDA-positive regulation of apoptotic process21487036
GO:0043519IEA-regulation of myosin II filament organization-
GO:0046777IDA-protein autophosphorylation18239682
GO:0046777TAS-protein autophosphorylation16756490
GO:0051893IDA-regulation of focal adhesion assembly23454120
GO:0071346IDA-cellular response to interferon-gamma18995835
GO:0090263IMP-positive regulation of canonical Wnt signaling pathway21454679
GO:0097190IEA-apoptotic signaling pathway-
GO:2000145TAS-regulation of cell motility-
GO:2000249IDA-regulation of actin cytoskeleton reorganization23454120
GO:2000249TAS-regulation of actin cytoskeleton reorganization-
GO:2001241IEA-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GRB14DAPK310798312242277 Reconstituted Complex
GRB14DAPK310914512242277 Reconstituted Complex
PRKCZDAPK311157612242277 Reconstituted Complex
PRKCZDAPK310798312242277 Reconstituted Complex
DAXXDAPK310798512917339 Affinity Capture-Western
DAXXDAPK310798312917339 Affinity Capture-Western
PAWRDAPK311110812917339 Affinity Capture-Western; Biochemical Activity; Two-hybrid
PAWRDAPK310798312917339 Affinity Capture-Western; Biochemical Activity; Two-hybrid
UBCDAPK311316418515077 Affinity Capture-Western
UBCDAPK310798318515077 Affinity Capture-Western
UBE2D3DAPK311317118515077 Affinity Capture-Western
UBE2D3DAPK310798318515077 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1203520
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-3026'