AutismKB 2.0

Annotation Details for SPRED1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SPRED1 ( FLJ33903,NFLS )
Gene Full Name: sprouty-related, EVH1 domain containing 1
Band: 15q14
Quick LinksEntrez ID:161742; OMIM: 609291; Uniprot ID:SPRE1_HUMAN; ENSEMBL ID: ENSG00000166068; HGNC ID: 20249
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus-
GO:0005829TAS-cytosol-
GO:0005886TAS-plasma membrane-
GO:0005901IEA-caveola-
GO ID Evidence Qualifier GO_term References
GO:0005173ISS-stem cell factor receptor binding-
GO:0005515IPI-protein binding15231748
GO:0019901IPI-protein kinase binding20736167
GO:0019902IDA-phosphatase binding19389623
GO:0030291ISS-protein serine/threonine kinase inhibitor activity20736167
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0000188ISS-inactivation of MAPK activity-
GO:0007275IEA-multicellular organism development-
GO:0008543TAS-fibroblast growth factor receptor signaling pathway-
GO:0010801IMP-negative regulation of peptidyl-threonine phosphorylation20736167
GO:0010923IDA-negative regulation of phosphatase activity19389623
GO:0043517ISS-positive regulation of DNA damage response, signal transduction by p53 class mediator20736167
GO:0090311ISS-regulation of protein deacetylation20736167
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SPRED1TESK111287517974561 Affinity Capture-Western
SPRED1TESK112780017974561 Affinity Capture-Western
SPRED1UBC12780017094949 Affinity Capture-Western
SPRED1UBC11316417094949 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2150016
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2338'