AutismKB 2.0

Annotation Details for ZFPM1


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Basic Information Top
Gene Symbol:ZFPM1 ( FOG,FOG1,ZNF408,ZNF89A )
Gene Full Name: zinc finger protein, multitype 1
Band: 16q24.2
Quick LinksEntrez ID:161882; OMIM: 601950; Uniprot ID:FOG1_HUMAN; ENSEMBL ID: ENSG00000179588; HGNC ID: 19762
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005654TAS-nucleoplasm-
GO:0005667IDA-transcription factor complex15920471
GO:0005737IEA-cytoplasm-
GO:0017053IDA-transcriptional repressor complex15920471
GO ID Evidence Qualifier GO_term References
GO:0000979IEA-RNA polymerase II core promoter sequence-specific DNA binding-
GO:0001078IDA-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding15920471
GO:0001085IPI-RNA polymerase II transcription factor binding11675338
GO:0001102IEA-RNA polymerase II activating transcription factor binding-
GO:0005515IPI-protein binding21047798
GO:0008134IPI-transcription factor binding12483298
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0002295IC-T-helper cell lineage commitment21646796
GO:0003151ISS-outflow tract morphogenesis-
GO:0003181ISS-atrioventricular valve morphogenesis-
GO:0003192ISS-mitral valve formation-
GO:0003195ISS-tricuspid valve formation-
GO:0006351IEA-transcription, DNA-templated-
GO:0007507IBA-heart development-
GO:0007596TAS-blood coagulation-
GO:0010724IDA-regulation of definitive erythrocyte differentiation15920471
GO:0010724IMP-regulation of definitive erythrocyte differentiation17207461
GO:0030218ISS-erythrocyte differentiation-
GO:0030219IBA-megakaryocyte differentiation-
GO:0030219ISS-megakaryocyte differentiation-
GO:0030220IGI-platelet formation11675338
GO:0030851IEA-granulocyte differentiation-
GO:0032091ISS-negative regulation of protein binding-
GO:0032642IEA-regulation of chemokine production-
GO:0035162ISS-embryonic hemopoiesis-
GO:0035855IEA-megakaryocyte development-
GO:0045078IDA-positive regulation of interferon-gamma biosynthetic process21646796
GO:0045403IDA-negative regulation of interleukin-4 biosynthetic process21646796
GO:0045599ISS-negative regulation of fat cell differentiation-
GO:0055008ISS-cardiac muscle tissue morphogenesis-
GO:0060318IEA-definitive erythrocyte differentiation-
GO:0060319IEA-primitive erythrocyte differentiation-
GO:0060377ISS-negative regulation of mast cell differentiation-
GO:0060412ISS-ventricular septum morphogenesis-
GO:0060413ISS-atrial septum morphogenesis-
GO:0071733ISS-transcriptional activation by promoter-enhancer looping-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ZFPM1GATA110889319513100 Affinity Capture-Western
ZFPM1GATA112780619513100 Affinity Capture-Western
ZFPM1GATA210889412483298 Affinity Capture-Western
ZFPM1GATA212780612483298 Affinity Capture-Western
ZFPM1TOP3B11445215231747 Two-hybrid
ZFPM1TOP3B12780615231747 Two-hybrid
ZFPM1GIPC111597815231747 Two-hybrid
ZFPM1GIPC112780615231747 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1095400
  • Data Attributes: MGI curated and HomoloGene calculated
No data