AutismKB 2.0

Annotation Details for DBH


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Basic Information Top
Gene Symbol:DBH ( DBM )
Gene Full Name: dopamine beta-hydroxylase (dopamine beta-monooxygenase)
Band: 9q34.2
Quick LinksEntrez ID:1621; OMIM: 609312; Uniprot ID:DOPO_HUMAN; ENSEMBL ID: ENSG00000123454; HGNC ID: 2689
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576NAS-extracellular region14718574
GO:0005615IDA-extracellular space7961964
GO:0005737TAS-cytoplasm3443096
GO:0016020TAS-membrane3443096
GO:0016021IEA-integral component of membrane-
GO:0030658IEA-transport vesicle membrane-
GO:0030667IDA-secretory granule membrane7961964
GO:0034466IEA-chromaffin granule lumen-
GO:0034774IDA-secretory granule lumen7961964
GO:0034774TAS-secretory granule lumen-
GO:0042584IEA-chromaffin granule membrane-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0003824TAS-catalytic activity3443096
GO:0004500IDA-dopamine beta-monooxygenase activity3443096
GO:0004500TAS-dopamine beta-monooxygenase activity-
GO:0005507IDA-copper ion binding7961964
GO:0031418IEA-L-ascorbic acid binding-
GO ID Evidence Qualifier GO_term References
GO:0001816IEA-cytokine production-
GO:0001974IEA-blood vessel remodeling-
GO:0001975IEA-response to amphetamine-
GO:0002443IEA-leukocyte mediated immunity-
GO:0006589IBA-octopamine biosynthetic process-
GO:0007268TAS-chemical synaptic transmission2880016
GO:0007613IEA-memory-
GO:0007626IEA-locomotory behavior-
GO:0008542IEA-visual learning-
GO:0042127IEA-regulation of cell proliferation-
GO:0042309IEA-homoiothermy-
GO:0042420IDA-dopamine catabolic process3443096
GO:0042421IEA-norepinephrine biosynthetic process-
GO:0042421IMP-norepinephrine biosynthetic process27148966
GO:0042423TAS-catecholamine biosynthetic process-
GO:0042593IEA-glucose homeostasis-
GO:0042596IEA-fear response-
GO:0042711IEA-maternal behavior-
GO:0045907IEA-positive regulation of vasoconstriction-
GO:0048149IEA-behavioral response to ethanol-
GO:0048265IEA-response to pain-
GO:0050900IEA-leukocyte migration-
GO:0055114IEA-oxidation-reduction process-
GO:2001236IEA-regulation of extrinsic apoptotic signaling pathway-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
DBHrs1611115 Gene overview in AlzGene
Gene Symbol Poly Names Gene overview in PDGene
DBHrs1108580, rs129882, rs1611115, rs4531, rs5320 Gene overview in PDGene
Gene Symbol Poly Names Gene overview in SZGene
DBHDBH_19bp-indel, DBH_2bpSTR, DBH_MspI, DBH_STR-downstream, DBH_STR-upstream, rs1076150, rs1108580, rs1108581, rs129882, rs129884, rs129885, rs1541333, rs1611115, rs2005663, rs2007153, rs2073837, rs2283123, rs2519148, rs3025399, rs4531, rs5320, rs732833, rs77905 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:94864
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-990621-3'