AutismKB 2.0

Annotation Details for AP2B1


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Basic Information Top
Gene Symbol:AP2B1 ( ADTB2,AP105B,AP2-BETA,CLAPB1,DKFZp781K0743 )
Gene Full Name: adaptor-related protein complex 2, beta 1 subunit
Band: 17q12
Quick LinksEntrez ID:163; OMIM: 601025; Uniprot ID:AP2B1_HUMAN; ENSEMBL ID: ENSG00000006125; HGNC ID: 563
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005802IEA-trans-Golgi network-
GO:0005829TAS-cytosol-
GO:0005886TAS-plasma membrane-
GO:0016020IDA-membrane19946888
GO:0030122IMP-AP-2 adaptor complex12086608
GO:0030122TAS-AP-2 adaptor complex12121421
GO:0030666TAS-endocytic vesicle membrane-
GO:0030669TAS-clathrin-coated endocytic vesicle membrane-
GO:0036020TAS-endolysosome membrane-
GO ID Evidence Qualifier GO_term References
GO:0005048TAS-signal sequence binding12121421
GO:0005515IPI-protein binding9341158
GO:0008565IEA-protein transporter activity-
GO:0030276IPI-clathrin binding19509056
GO:0030276TAS-clathrin binding12121421
GO:0032403IEA-protein complex binding-
GO:0035615TAScontributes_toclathrin adaptor activity12121421
GO ID Evidence Qualifier GO_term References
GO:0003281IEA-ventricular septum development-
GO:0006886IEA-intracellular protein transport-
GO:0007018TAS-microtubule-based movement-
GO:0019886TAS-antigen processing and presentation of exogenous peptide antigen via MHC class II-
GO:0032802TAS-low-density lipoprotein particle receptor catabolic process-
GO:0034383TAS-low-density lipoprotein particle clearance-
GO:0035904IEA-aorta development-
GO:0048013TAS-ephrin receptor signaling pathway-
GO:0048268IEA-clathrin coat assembly-
GO:0050690TAS-regulation of defense response to virus by virus-
GO:0060071TAS-Wnt signaling pathway, planar cell polarity pathway-
GO:0060976IEA-coronary vasculature development-
GO:0061024TAS-membrane organization-
GO:0072583TAS-clathrin-dependent endocytosis12121421
GO:0099590IEA-neurotransmitter receptor internalization-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ARRB2AP2B110690210097102 12070169 Reconstituted Complex; Two-hybrid
ARRB2AP2B110667210097102 12070169 Reconstituted Complex; Two-hybrid
LDLRAP1AP2B110667212221107 16189514 Reconstituted Complex; Two-hybrid
LDLRAP1AP2B111756112221107 16189514 Reconstituted Complex; Two-hybrid
BUB1BAP2B110667212419313 Reconstituted Complex; Two-hybrid
BUB1BAP2B110716612419313 Reconstituted Complex; Two-hybrid
TGFBR1AP2B110667212429842 Affinity Capture-Western
TGFBR1AP2B111290412429842 Affinity Capture-Western
TGFBR2AP2B111290612429842 Affinity Capture-Western; Two-hybrid
TGFBR2AP2B110667212429842 Affinity Capture-Western; Two-hybrid
CLINT1AP2B111503812429846 Reconstituted Complex
CLINT1AP2B110667212429846 Reconstituted Complex
AP1M2AP2B111536416189514 Affinity Capture-Western; Two-hybrid
AP1M2AP2B110667216189514 Affinity Capture-Western; Two-hybrid
MEA1AP2B110667216189514 Affinity Capture-Western; Two-hybrid
MEA1AP2B111036516189514 Affinity Capture-Western; Two-hybrid
AP2M1AP2B110758716189514 Two-hybrid
AP2M1AP2B110667216189514 Two-hybrid
RIBC2AP2B110667216189514 Two-hybrid
RIBC2AP2B111758116189514 Two-hybrid
TUBGCP4AP2B111807816189514 Two-hybrid
TUBGCP4AP2B110667216189514 Two-hybrid
MLH1AP2B110667216189514 Two-hybrid
MLH1AP2B111043816189514 Two-hybrid
NUP54AP2B111975916189514 Two-hybrid
NUP54AP2B110667216189514 Two-hybrid
TERF2IPAP2B110667216189514 Two-hybrid
TERF2IPAP2B111994216189514 Two-hybrid
FAM46CAP2B112020516189514 Two-hybrid
FAM46CAP2B110667216189514 Two-hybrid
THAP1AP2B110667216189514 Two-hybrid
THAP1AP2B112044816189514 Two-hybrid
NECAP2AP2B112083216189514 Two-hybrid
NECAP2AP2B110667216189514 Two-hybrid
DHX58AP2B110667216189514 Two-hybrid
DHX58AP2B112255316189514 Two-hybrid
AP1M1AP2B111442116189514 Two-hybrid
AP1M1AP2B110667216189514 Two-hybrid
ATP6V1G1AP2B111492216189514 Two-hybrid
ATP6V1G1AP2B110667216189514 Two-hybrid
KIAA0408AP2B110667216189514 Two-hybrid
KIAA0408AP2B111507816189514 Two-hybrid
POM121AP2B110667216189514 Two-hybrid
POM121AP2B111521416189514 Two-hybrid
RNPS1AP2B111612517353931 Affinity Capture-MS
RNPS1AP2B110667217353931 Affinity Capture-MS
OSBPL10AP2B112538519615732 Affinity Capture-MS
OSBPL10AP2B110667219615732 Affinity Capture-MS
APCAP2B110667220936779 Two-hybrid
APCAP2B110682120936779 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1919020
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-6564'