AutismKB 2.0

Annotation Details for DCC


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Basic Information Top
Gene Symbol:DCC ( CRC18,CRCR1,IGDCC1 )
Gene Full Name: deleted in colorectal carcinoma
Band: 18q21.2
Quick LinksEntrez ID:1630; OMIM: 120470; Uniprot ID:DCC_HUMAN; ENSEMBL ID: ENSG00000187323; HGNC ID: 2701
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0005886TAS-plasma membrane-
GO:0016021IEA-integral component of membrane-
GO:0030424IEA-axon-
GO ID Evidence Qualifier GO_term References
GO:0004888TAS-transmembrane signaling receptor activity8861902
GO:0005042IEA-netrin receptor activity-
GO:0005515IPI-protein binding11527412
GO ID Evidence Qualifier GO_term References
GO:0001764IEA-neuron migration-
GO:0006915TAS-apoptotic process9796814
GO:0007409TAS-axonogenesis8861902
GO:0007411TAS-axon guidance-
GO:0010977TAS-negative regulation of neuron projection development19616629
GO:0021965IEA-spinal cord ventral commissure morphogenesis-
GO:0033563IEA-dorsal/ventral axon guidance-
GO:0033564IEA-anterior/posterior axon guidance-
GO:0038007IEA-netrin-activated signaling pathway-
GO:0048671TAS-negative regulation of collateral sprouting19616629
GO:0097192TAS-extrinsic apoptotic signaling pathway in absence of ligand-
GO:1901214IMP-regulation of neuron death21085126
GO:2000171TAS-negative regulation of dendrite development19616629
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DCCAR10799812864730 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
DCCAR10686212864730 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
DCCCASP310728611248093 Affinity Capture-Western; Two-hybrid
DCCCASP310799811248093 Affinity Capture-Western; Two-hybrid
DCCCASP910799811248093 Affinity Capture-Western
DCCCASP910729211248093 Affinity Capture-Western
SIAH1DCC1123729858595 Reconstituted Complex
SIAH1DCC1079989858595 Reconstituted Complex
NTN1DCC1148169950216 12810718 Reconstituted Complex
NTN1DCC1079989950216 12810718 Reconstituted Complex
MAZDCC11032011527412 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MAZDCC10799811527412 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MAPK3DCC11158111986622 Two-hybrid
MAPK3DCC10799811986622 Two-hybrid
APPL1DCC11752212011067 Affinity Capture-Western; Two-hybrid
APPL1DCC10799812011067 Affinity Capture-Western; Two-hybrid
NCK1DCC11077012149262 Affinity Capture-Western
NCK1DCC10799812149262 Affinity Capture-Western
PTK2DCC11171915494733 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PTK2DCC10799815494733 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PTK2BDCC10848015494733 Reconstituted Complex
PTK2BDCC10799815494733 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
DCCrs17468382 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:94869
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-011101-2'