AutismKB 2.0

Annotation Details for DCN


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Basic Information Top
Gene Symbol:DCN ( CSCD,DSPG2,PG40,PGII,PGS2,SLRR1B )
Gene Full Name: decorin
Band: 12q21.33
Quick LinksEntrez ID:1634; OMIM: 125255; Uniprot ID:PGS2_HUMAN; ENSEMBL ID: ENSG00000011465; HGNC ID: 2705
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005578IEA-proteinaceous extracellular matrix-
GO:0005589IEA-collagen type VI trimer-
GO:0005615IDA-extracellular space20551380
GO:0005737IBA-cytoplasm-
GO:0005796TAS-Golgi lumen-
GO:0031012IDAcolocalizes_withextracellular matrix20551380
GO:0031012ISScolocalizes_withextracellular matrix22261194
GO:0043202TAS-lysosomal lumen-
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0004860IBA-protein kinase inhibitor activity-
GO:0005515IPI-protein binding1747115
GO:0005518IEA-collagen binding-
GO:0005539IEA-glycosaminoglycan binding-
GO:0047485IEA-protein N-terminus binding-
GO:0050840IEA-extracellular matrix binding-
GO ID Evidence Qualifier GO_term References
GO:0001822IEA-kidney development-
GO:0001890IEA-placenta development-
GO:0006469IBA-negative regulation of protein kinase activity-
GO:0007519IEA-skeletal muscle tissue development-
GO:0007568IEA-aging-
GO:0009612IEA-response to mechanical stimulus-
GO:0009887TAS-animal organ morphogenesis7961765
GO:0010508IDA-positive regulation of autophagy23798385
GO:0010596IDA-negative regulation of endothelial cell migration23798385
GO:0014068IDA-positive regulation of phosphatidylinositol 3-kinase signaling23798385
GO:0016239IDA-positive regulation of macroautophagy23798385
GO:0016239IGI-positive regulation of macroautophagy23798385
GO:0016525IDA-negative regulation of angiogenesis23978385
GO:0019221IBA-cytokine-mediated signaling pathway-
GO:0019800IEA-peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan-
GO:0022617TAS-extracellular matrix disassembly-
GO:0030198TAS-extracellular matrix organization-
GO:0030203TAS-glycosaminoglycan metabolic process-
GO:0030206TAS-chondroitin sulfate biosynthetic process-
GO:0030207TAS-chondroitin sulfate catabolic process-
GO:0030208TAS-dermatan sulfate biosynthetic process-
GO:0032496IEA-response to lipopolysaccharide-
GO:0042060IEA-wound healing-
GO:0045944IGI-positive regulation of transcription from RNA polymerase II promoter23798385
GO:0046426IBA-negative regulation of JAK-STAT cascade-
GO:0051901IGI-positive regulation of mitochondrial depolarization23798385
GO:0090141IGI-positive regulation of mitochondrial fission23798385
GO:1900747IDA-negative regulation of vascular endothelial growth factor signaling pathway23798385
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DCNAHSG10670012071714 Reconstituted Complex
DCNAHSG10800212071714 Reconstituted Complex
DCNC1QA1071731431141 Reconstituted Complex
DCNC1QA1080021431141 Reconstituted Complex
DCNCOL6A11076881544908 Reconstituted Complex
DCNCOL6A11080021544908 Reconstituted Complex
TGFB1DCN1080027798269 8093006 9675033 Reconstituted Complex
TGFB1DCN1128987798269 8093006 9675033 Reconstituted Complex
COL14A1DCN1080029252349 Reconstituted Complex
COL14A1DCN1132199252349 Reconstituted Complex
TGFB2DCN1080029675033 Reconstituted Complex
TGFB2DCN1129009675033 Reconstituted Complex
EGFRDCN1080029988678 12105206 Reconstituted Complex; Two-hybrid
EGFRDCN1082769988678 12105206 Reconstituted Complex; Two-hybrid
PLA2G2ADCN11133710747008 Reconstituted Complex
PLA2G2ADCN10800210747008 Reconstituted Complex
ELNDCN10832111723132 Reconstituted Complex
ELNDCN10800211723132 Reconstituted Complex
FLNADCN10860512106908 Reconstituted Complex
FLNADCN10800212106908 Reconstituted Complex
TNFDCN10800212387878 Reconstituted Complex
TNFDCN11297912387878 Reconstituted Complex
SFTPDDCN11233912730206 Reconstituted Complex
SFTPDDCN10800212730206 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:94872
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-010102-1'