AutismKB 2.0

Annotation Details for DDC


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Basic Information Top
Gene Symbol:DDC ( AADC )
Gene Full Name: dopa decarboxylase (aromatic L-amino acid decarboxylase)
Band: 7p12.2-p12.1
Quick LinksEntrez ID:1644; OMIM: 107930; Uniprot ID:DDC_HUMAN; ENSEMBL ID: ENSG00000132437; HGNC ID: 2719
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0008021IEA-synaptic vesicle-
GO:0030424IEA-axon-
GO:0043025IEA-neuronal cell body-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0004058IDA-aromatic-L-amino-acid decarboxylase activity16338639
GO:0004058TAS-aromatic-L-amino-acid decarboxylase activity-
GO:0005515IPI-protein binding12864730
GO:0016597IEA-amino acid binding-
GO:0019899IPI-enzyme binding19703902
GO:0019904IEA-protein domain specific binding-
GO:0030170IEA-pyridoxal phosphate binding-
GO:0036468IDA-L-dopa decarboxylase activity19703902
GO ID Evidence Qualifier GO_term References
GO:0006520IEA-cellular amino acid metabolic process-
GO:0007623IEA-circadian rhythm-
GO:0010259IEA-multicellular organism aging-
GO:0015842IEA-aminergic neurotransmitter loading into synaptic vesicle-
GO:0033076IEA-isoquinoline alkaloid metabolic process-
GO:0035690IEA-cellular response to drug-
GO:0042416IEA-dopamine biosynthetic process-
GO:0042423TAS-catecholamine biosynthetic process-
GO:0042427IEA-serotonin biosynthetic process-
GO:0046219TAS-indolalkylamine biosynthetic process-
GO:0046684IEA-response to pyrethroid-
GO:0052314IEA-phytoalexin metabolic process-
GO:0071312IEA-cellular response to alkaloid-
GO:0071363IEA-cellular response to growth factor stimulus-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
DDCrs11575553, rs3829897, rs6263 Gene overview in PDGene
Gene Symbol Poly Names Gene overview in SZGene
DDCDDC_1bp-indel, DDC_4bp-indel, DDC_STR, rs11238214, rs11575542, rs11575553, rs1451373, rs1451374, rs1470747, rs3823674, rs3829897, rs4947954, rs6263, rs6593010, rs921450, rs998850 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:94876
  • Data Attributes: MGI curated and HomoloGene calculated