AutismKB 2.0

Annotation Details for AES


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Basic Information Top
Gene Symbol:AES ( AES-1,AES-2,ESP1,GRG,GRG5,TLE5 )
Gene Full Name: amino-terminal enhancer of split
Band: 19p13.3
Quick LinksEntrez ID:166; OMIM: 600188; Uniprot ID:AES_HUMAN; ENSEMBL ID: ENSG00000104964; HGNC ID: 307
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus22952044
GO ID Evidence Qualifier GO_term References
GO:0003714IDA-transcription corepressor activity19460168
GO:0003714IPI-transcription corepressor activity10660609
GO:0005515IPI-protein binding10660609
GO ID Evidence Qualifier GO_term References
GO:0000122IMP-negative regulation of transcription from RNA polymerase II promoter10660609
GO:0006351IEA-transcription, DNA-templated-
GO:0007275TAS-multicellular organism development8365415
GO:0009887TAS-animal organ morphogenesis9809752
GO:0010629IMP-negative regulation of gene expression15006356
GO:0016055IEA-Wnt signaling pathway-
GO:0032091IDA-negative regulation of protein binding15489227
GO:0045892IDA-negative regulation of transcription, DNA-templated19460168
GO:0060761IMP-negative regulation of response to cytokine stimulus15489227
GO:0070555IDA-response to interleukin-115489227
GO:0090090IDA-negative regulation of canonical Wnt signaling pathway19460168
GO:2000210IMP-positive regulation of anoikis15006356
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RELAAES11190210660609 15489227 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RELAAES10667510660609 15489227 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RUNX1AES10667510825294 Two-hybrid
RUNX1AES10730910825294 Two-hybrid
AESAES10667511266540 Two-hybrid
HNF1AAES11278911266540 Two-hybrid
HNF1AAES10667511266540 Two-hybrid
ARAES10667511416139 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ARAES10686211416139 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
GTF2E1AES10667511416139 Reconstituted Complex
GTF2E1AES10921511416139 Reconstituted Complex
HMGB1AES10938911748221 Reconstituted Complex
HMGB1AES10667511748221 Reconstituted Complex
SIX6AES10667512441302 Reconstituted Complex; Two-hybrid
SIX6AES11103412441302 Reconstituted Complex; Two-hybrid
SIX3AES10667512441302 Reconstituted Complex; Two-hybrid
SIX3AES11238712441302 Reconstituted Complex; Two-hybrid
PTRH2AES10667515006356 Affinity Capture-Western; Two-hybrid
PTRH2AES11965915006356 Affinity Capture-Western; Two-hybrid
MED31AES11921116169070 Two-hybrid
MED31AES10667516169070 Two-hybrid
SH3GL3AES11235416169070 Two-hybrid
SH3GL3AES10667516169070 Two-hybrid
HNRNPABAES10667517353931 Affinity Capture-MS
HNRNPABAES10942317353931 Affinity Capture-MS
STYXL1AES10667517353931 Affinity Capture-MS
STYXL1AES11966317353931 Affinity Capture-MS
TLE1AES11294317353931 Affinity Capture-MS
TLE1AES10667517353931 Affinity Capture-MS
TLE3AES11294517353931 Affinity Capture-MS
TLE3AES10667517353931 Affinity Capture-MS
MAPK14AES10667520936779 Two-hybrid
MAPK14AES10781920936779 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:95806
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1409'