AutismKB 2.0

Annotation Details for DFFA


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Basic Information Top
Gene Symbol:DFFA ( DFF-45,DFF1,ICAD )
Gene Full Name: DNA fragmentation factor, 45kDa, alpha polypeptide
Band: 1p36.22
Quick LinksEntrez ID:1676; OMIM: 601882; Uniprot ID:DFFA_HUMAN; ENSEMBL ID: ENSG00000160049; HGNC ID: 2772
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin19882353
GO:0005634IDA-nucleus15572351
GO:0005654TAS-nucleoplasm-
GO:0005811IBANOTlipid particle-
GO:0005829IDA-cytosol9108473
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding19882353
GO:0019904IPI-protein domain specific binding11371636
GO:0044183IPI-protein binding involved in protein folding19944011
GO:0060703IMP-deoxyribonuclease inhibitor activity19944011
GO ID Evidence Qualifier GO_term References
GO:0006309TAS-apoptotic DNA fragmentation-
GO:0032076IMP-negative regulation of deoxyribonuclease activity19944011
GO:0043065IEA-positive regulation of apoptotic process-
GO:0061077IMP-chaperone-mediated protein folding19944011
GO:0070242IEA-thymocyte apoptotic process-
GO:1900118IDA-negative regulation of execution phase of apoptosis9564035
GO:1902511IDA-negative regulation of apoptotic DNA fragmentation15572351
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DFFABAK110705417353931 Affinity Capture-MS
DFFABAK110804017353931 Affinity Capture-MS
DFFBDFFA10804010527860 17353931 Affinity Capture-MS; Affinity Capture-Western
DFFBDFFA10804110527860 17353931 Affinity Capture-MS; Affinity Capture-Western
CIDEBDFFA11802710619428 Reconstituted Complex
CIDEBDFFA10804010619428 Reconstituted Complex
EWSR1DFFA10843116189514 Two-hybrid
EWSR1DFFA10804016189514 Two-hybrid
NECAB2DFFA12003516189514 Two-hybrid
NECAB2DFFA10804016189514 Two-hybrid
NAP1L5DFFA10804017353931 Affinity Capture-MS
NAP1L5DFFA12934417353931 Affinity Capture-MS
MCCDFFA11033317353931 Affinity Capture-MS
MCCDFFA10804017353931 Affinity Capture-MS
TMBIM4DFFA10804017353931 Affinity Capture-MS
TMBIM4DFFA11965317353931 Affinity Capture-MS
YWHAZDFFA11336617353931 Affinity Capture-MS
YWHAZDFFA10804017353931 Affinity Capture-MS
HERC1DFFA11443917353931 Affinity Capture-MS
HERC1DFFA10804017353931 Affinity Capture-MS
USP15DFFA11528317353931 Affinity Capture-MS
USP15DFFA10804017353931 Affinity Capture-MS
PRKAA2DFFA11155020562859 Affinity Capture-MS
PRKAA2DFFA10804020562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1196227
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040718-376'