AutismKB 2.0

Annotation Details for DHCR7


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Basic Information Top
Gene Symbol:DHCR7 ( SLOS )
Gene Full Name: 7-dehydrocholesterol reductase
Band: 11q13.4
Quick LinksEntrez ID:1717; OMIM: 602858; Uniprot ID:DHCR7_HUMAN; ENSEMBL ID: ENSG00000172893; HGNC ID: 2860
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005640IDA-nuclear outer membrane9878250
GO:0005783IDA-endoplasmic reticulum9878250
GO:0005789TAS-endoplasmic reticulum membrane-
GO:0005829IDA-cytosol-
GO:0016020IDA-membrane19946888
GO:0030176IBA-integral component of endoplasmic reticulum membrane-
GO ID Evidence Qualifier GO_term References
GO:0009918IBA-sterol delta7 reductase activity-
GO:0047598EXP-7-dehydrocholesterol reductase activity9465114
GO:0047598IDA-7-dehydrocholesterol reductase activity9465114
GO:0050661ISS-NADP binding-
GO ID Evidence Qualifier GO_term References
GO:0001568IEA-blood vessel development-
GO:0006695IMP-cholesterol biosynthetic process9465114
GO:0009791IEA-post-embryonic development-
GO:0016132IBA-brassinosteroid biosynthetic process-
GO:0030154IEA-cell differentiation-
GO:0030324IEA-lung development-
GO:0033489TAS-cholesterol biosynthetic process via desmosterol-
GO:0033490TAS-cholesterol biosynthetic process via lathosterol-
GO:0035264IEA-multicellular organism growth-
GO:0042127IEA-regulation of cell proliferation-
GO:0045540TAS-regulation of cholesterol biosynthetic process-
GO:0055114IEA-oxidation-reduction process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TOR1ADHCR710806317353931 Affinity Capture-MS
TOR1ADHCR710819317353931 Affinity Capture-MS
FADS1DHCR710806317353931 Affinity Capture-MS
FADS1DHCR711018017353931 Affinity Capture-MS
NDNDHCR710806317353931 Affinity Capture-MS
NDNDHCR711077217353931 Affinity Capture-MS
ACP6DHCR710806317353931 Affinity Capture-MS
ACP6DHCR711937817353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1298378
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030912-9'