AutismKB 2.0

Annotation Details for NQO1


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Basic Information Top
Gene Symbol:NQO1 ( DHQU,DIA4,DTD,NMOR1,NMORI,QR1 )
Gene Full Name: NAD(P)H dehydrogenase, quinone 1
Band: 16q22.1
Quick LinksEntrez ID:1728; OMIM: 125860; Uniprot ID:NQO1_HUMAN; ENSEMBL ID: ENSG00000181019; HGNC ID: 2874
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737TAS-cytoplasm2843525
GO:0005829IDA-cytosol10945627
GO:0005829TAS-cytosol-
GO:0043025IEA-neuronal cell body-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0003955IEA-NAD(P)H dehydrogenase (quinone) activity-
GO:0004128TAS-cytochrome-b5 reductase activity, acting on NAD(P)H9579781
GO:0004784IEA-superoxide dismutase activity-
GO:0005515IPI-protein binding18388957
GO:0042802IPI-identical protein binding25143260
GO ID Evidence Qualifier GO_term References
GO:0006521TAS-regulation of cellular amino acid metabolic process-
GO:0006805TAS-xenobiotic metabolic process10393963
GO:0006809TAS-nitric oxide biosynthetic process9579781
GO:0007271TAS-synaptic transmission, cholinergic9579781
GO:0007568IEA-aging-
GO:0007584IEA-response to nutrient-
GO:0009636TAS-response to toxic substance10393963
GO:0019430IEA-removal of superoxide radicals-
GO:0032355IEA-response to estradiol-
GO:0043066IEA-negative regulation of apoptotic process-
GO:0043086IEA-negative regulation of catalytic activity-
GO:0043525IEA-positive regulation of neuron apoptotic process-
GO:0045471IEA-response to ethanol-
GO:0055114IEA-oxidation-reduction process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NQO1NQO110807210543876 Co-crystal Structure
HSPA4NQO110954011821413 Affinity Capture-Western
HSPA4NQO110807211821413 Affinity Capture-Western
ING1NQO110983318388957 Reconstituted Complex
ING1NQO110807218388957 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
NQO1rs1800566 Gene overview in AlzGene
Gene Symbol Poly Names Gene overview in PDGene
NQO1rs1800566 Gene overview in PDGene
Gene Symbol Poly Names Gene overview in SZGene
NQO1rs1800566 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:103187
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-1226'