AutismKB 2.0

Annotation Details for DLG2


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Basic Information Top
Gene Symbol:DLG2 ( DKFZp781D1854,DKFZp781E0954,FLJ37266,MGC131811,PSD-93,PSD93,chapsyn-110 )
Gene Full Name: discs, large homolog 2 (Drosophila)
Band: 11q14.1
Quick LinksEntrez ID:1740; OMIM: 603583; Uniprot ID:DLG2_HUMAN; ENSEMBL ID: ENSG00000150672; HGNC ID: 2901
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0005886TAS-plasma membrane8755482
GO:0008076ISScolocalizes_withvoltage-gated potassium channel complex-
GO:0008328IBAcolocalizes_withionotropic glutamate receptor complex-
GO:0014069IBA-postsynaptic density-
GO:0016020ISS-membrane-
GO:0016323IBANOTbasolateral plasma membrane-
GO:0030054IEA-cell junction-
GO:0044224ISS-juxtaparanode region of axon-
GO:0045211IBA-postsynaptic membrane-
GO ID Evidence Qualifier GO_term References
GO:0004385TAS-guanylate kinase activity8755482
GO:0005515IPI-protein binding15304517
GO:0019900IDA-kinase binding21119615
GO:0035255IBA-ionotropic glutamate receptor binding-
GO ID Evidence Qualifier GO_term References
GO:0007268IBA-chemical synaptic transmission-
GO:0007399IBA-nervous system development-
GO:0010923IDA-negative regulation of phosphatase activity19389623
GO:0019233IEA-sensory perception of pain-
GO:0043113IBA-receptor clustering-
GO:0045197IBANOTestablishment or maintenance of epithelial cell apical/basal polarity-
GO:0046037IEA-GMP metabolic process-
GO:0046710IEA-GDP metabolic process-
GO:0097120IBA-receptor localization to synapse-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DLG2ATP2B210808411274188 Affinity Capture-Western
DLG2ATP2B210698111274188 Affinity Capture-Western
DLG2ATP2B410808411274188 Affinity Capture-Western
DLG2ATP2B410698311274188 Affinity Capture-Western
NOS1DLG21080848625413 Two-hybrid
NOS1DLG21109058625413 Two-hybrid
DLG4DLG21080849182804 Affinity Capture-Western
DLG4DLG21080869182804 Affinity Capture-Western
GRIN2BDLG21080849278515 11997254 Affinity Capture-Western; Two-hybrid
GRIN2BDLG21091619278515 11997254 Affinity Capture-Western; Two-hybrid
NLGN1DLG21080849278515 Two-hybrid
NLGN1DLG21165389278515 Two-hybrid
GRIN2ADLG21080849278515 Two-hybrid
GRIN2ADLG21091609278515 Two-hybrid
NLGN3DLG21080849278515 Two-hybrid
NLGN3DLG21199449278515 Two-hybrid
NLGN2DLG21080849278515 Two-hybrid
NLGN2DLG21216119278515 Two-hybrid
ERBB4DLG210808410725395 Two-hybrid
ERBB4DLG210837810725395 Two-hybrid
DYNLL2DLG210808410844022 Affinity Capture-Western
DYNLL2DLG212668010844022 Affinity Capture-Western
DYNLL1DLG210808410844022 Affinity Capture-Western
DYNLL1DLG211420610844022 Affinity Capture-Western
DLGAP1DLG210808410844022 Affinity Capture-Western
DLGAP1DLG211466010844022 Affinity Capture-Western
SEMA4CDLG210808411134026 Two-hybrid
SEMA4CDLG212025411134026 Two-hybrid
GUCY1A2DLG210808411572861 Affinity Capture-Western
GUCY1A2DLG210923211572861 Affinity Capture-Western
KCNA4DLG210808411997254 Affinity Capture-Western
KCNA4DLG210994211997254 Affinity Capture-Western
KCNJ4DLG210808411997254 Affinity Capture-Western
KCNJ4DLG210996311997254 Affinity Capture-Western
LRP2DLG210808412713445 Two-hybrid
LRP2DLG211021612713445 Two-hybrid
KCNJ12DLG210808415024025 Affinity Capture-MS; Affinity Capture-Western
KCNJ12DLG210997015024025 Affinity Capture-MS; Affinity Capture-Western
Gene Symbol Interactant Interaction ID References Description
DLGAP1DLG229653111122378 DAP-1 interacts with Chapsyn-110.
ERBB4DLG214976110725395 ErbB-4 interacts with CHAPSYN-110.
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
DLG2rs10501570 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:1344351
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050221-3'