AutismKB 2.0

Annotation Details for DLX1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DLX1 ( - )
Gene Full Name: distal-less homeobox 1
Band: 2q31.1
Quick LinksEntrez ID:1745; OMIM: 600029; Uniprot ID:DLX1_HUMAN; ENSEMBL ID: ENSG00000144355; HGNC ID: 2914
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus14671321
GO ID Evidence Qualifier GO_term References
GO:0000977IEA-RNA polymerase II regulatory region sequence-specific DNA binding-
GO:0003682IEA-chromatin binding-
GO:0005515IPI-protein binding14671321
GO ID Evidence Qualifier GO_term References
GO:0000122IMP-negative regulation of transcription from RNA polymerase II promoter14671321
GO:0006351IEA-transcription, DNA-templated-
GO:0009954IEA-proximal/distal pattern formation-
GO:0021544IEA-subpallium development-
GO:0021766IEA-hippocampus development-
GO:0021882IEA-regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment-
GO:0021893IEA-cerebral cortex GABAergic interneuron fate commitment-
GO:0030514IMP-negative regulation of BMP signaling pathway14671321
GO:0042475IEA-odontogenesis of dentin-containing tooth-
GO:0043524IEA-negative regulation of neuron apoptotic process-
GO:0045597ISS-positive regulation of cell differentiation-
GO:0045746IEA-negative regulation of Notch signaling pathway-
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter14671321
GO:0045944ISS-positive regulation of transcription from RNA polymerase II promoter-
GO:0046533ISS-negative regulation of photoreceptor cell differentiation-
GO:0048706IEA-embryonic skeletal system development-
GO:0048715IEA-negative regulation of oligodendrocyte differentiation-
GO:0071560IMP-cellular response to transforming growth factor beta stimulus14671321
GO:0071773IMP-cellular response to BMP stimulus14671321
GO:1902871ISS-positive regulation of amacrine cell differentiation-
GO:1903845IMP-negative regulation of cellular response to transforming growth factor beta stimulus14671321
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SMAD4DLX110808914671321 Affinity Capture-Western
SMAD4DLX111026414671321 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
DLX1rs788173, rs813720 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:94901
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-990415-48'