AutismKB 2.0

Annotation Details for DLX2


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Basic Information Top
Gene Symbol:DLX2 ( TES-1,TES1 )
Gene Full Name: distal-less homeobox 2
Band: 2q31.1
Quick LinksEntrez ID:1746; OMIM: 126255; Uniprot ID:DLX2_HUMAN; ENSEMBL ID: ENSG00000115844; HGNC ID: 2915
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO ID Evidence Qualifier GO_term References
GO:0000977IEA-RNA polymerase II regulatory region sequence-specific DNA binding-
GO:0001228IEA-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-
GO:0003682IEA-chromatin binding-
GO:0003700TAS-transcription factor activity, sequence-specific DNA binding1354641
GO:0003727IEA-single-stranded RNA binding-
GO:0005515IPI-protein binding25416956
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0007420TAS-brain development7590232
GO:0009954IEA-proximal/distal pattern formation-
GO:0021544IEA-subpallium development-
GO:0021766IEA-hippocampus development-
GO:0021772IEA-olfactory bulb development-
GO:0021882IEA-regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment-
GO:0021893IEA-cerebral cortex GABAergic interneuron fate commitment-
GO:0042475IEA-odontogenesis of dentin-containing tooth-
GO:0045597ISS-positive regulation of cell differentiation-
GO:0045746IEA-negative regulation of Notch signaling pathway-
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
GO:0046533ISS-negative regulation of photoreceptor cell differentiation-
GO:0048701IEA-embryonic cranial skeleton morphogenesis-
GO:0048715IEA-negative regulation of oligodendrocyte differentiation-
GO:0048755IEA-branching morphogenesis of a nerve-
GO:0051216IEA-cartilage development-
GO:1902871ISS-positive regulation of amacrine cell differentiation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DLX2DLX21080909111364 Reconstituted Complex
DLX5DLX21080909111364 Reconstituted Complex
DLX5DLX21080939111364 Reconstituted Complex
HOXC8DLX21080909111364 Reconstituted Complex
HOXC8DLX21094649111364 Reconstituted Complex
MSX2DLX21080909111364 Reconstituted Complex
MSX2DLX21105949111364 Reconstituted Complex
MSX1DLX21080909111364 Reconstituted Complex; Two-hybrid
MSX1DLX21105939111364 Reconstituted Complex; Two-hybrid
XRCC6DLX210809011279128 Reconstituted Complex
XRCC6DLX210882211279128 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:94902
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-980526-18'