AutismKB 2.0

Annotation Details for DNM1


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Basic Information Top
Gene Symbol:DNM1 ( DNM )
Gene Full Name: dynamin 1
Band: 9q34.11
Quick LinksEntrez ID:1759; OMIM: 602377; Uniprot ID:DYN1_HUMAN; ENSEMBL ID: ENSG00000106976; HGNC ID: 2972
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001917IEA-photoreceptor inner segment-
GO:0005874IEA-microtubule-
GO:0005886TAS-plasma membrane-
GO:0030117IEA-membrane coat-
GO:0031966IBA-mitochondrial membrane-
GO:0043209IEA-myelin sheath-
GO:0045202IEA-synapse-
GO:0070062IDA-extracellular exosome23533145
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22681889
GO:0003924IBA-GTPase activity-
GO:0005515IPI-protein binding10206341
GO:0005525IEA-GTP binding-
GO:0008017IBA-microtubule binding-
GO:0019901ISS-protein kinase binding-
GO:0042802IPI-identical protein binding20700106
GO:0046983IEA-protein dimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0000266IBA-mitochondrial fission-
GO:0003374IBA-dynamin family protein polymerization involved in mitochondrial fission-
GO:0006897IMP-endocytosis19706678
GO:0006897TAS-endocytosis16648839
GO:0006898IMP-receptor-mediated endocytosis10521508
GO:0007032IMP-endosome organization19706678
GO:0007605IEA-sensory perception of sound-
GO:0008344IEA-adult locomotory behavior-
GO:0016185IEA-synaptic vesicle budding from presynaptic endocytic zone membrane-
GO:0048013TAS-ephrin receptor signaling pathway-
GO:0051262IEA-protein tetramerization-
GO:0051932IEA-synaptic transmission, GABAergic-
GO:0061025IBA-membrane fusion-
GO:1901998IEA-toxin transport-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DNM1AMPH1080999148966 9280305 9341169 9348539 11877424 Affinity Capture-Western; Reconstituted Complex
DNM1AMPH1067709148966 9280305 9341169 9348539 11877424 Affinity Capture-Western; Reconstituted Complex
DNM1DNM11080997634088 Co-crystal Structure
GRB2DNM11080998119878 9009162 Affinity Capture-Western; Far Western; Reconstituted Complex
GRB2DNM11091428119878 9009162 Affinity Capture-Western; Far Western; Reconstituted Complex
SH3GL2DNM11080999341169 12456676 Reconstituted Complex
SH3GL2DNM11123539341169 12456676 Reconstituted Complex
FERDNM11080999722593 Co-fractionation
FERDNM11085329722593 Co-fractionation
MAP3K10DNM11080999742220 Reconstituted Complex
MAP3K10DNM11104409742220 Reconstituted Complex
NCK1DNM110809910206341 Affinity Capture-Western; Reconstituted Complex
NCK1DNM111077010206341 Affinity Capture-Western; Reconstituted Complex
SH3GL1DNM110809910764144 Reconstituted Complex
SH3GL1DNM111235210764144 Reconstituted Complex
CABIN1DNM110809910931822 Affinity Capture-Western
CABIN1DNM111707010931822 Affinity Capture-Western
PACSIN1DNM111901811082044 15252009 Affinity Capture-Western; Reconstituted Complex
PACSIN1DNM110809911082044 15252009 Affinity Capture-Western; Reconstituted Complex
PACSIN2DNM110809911082044 Reconstituted Complex
PACSIN2DNM111641311082044 Reconstituted Complex
PACSIN3DNM110809911082044 Reconstituted Complex
PACSIN3DNM111889611082044 Reconstituted Complex
DYRK1ADNM110809911877424 Reconstituted Complex
DYRK1ADNM110819211877424 Reconstituted Complex
CLINT1DNM110809912429846 Reconstituted Complex
CLINT1DNM111503812429846 Reconstituted Complex
SH3GLB1DNM110809912456676 Reconstituted Complex
SH3GLB1DNM111928912456676 Reconstituted Complex
DNMBPDNM110809914506234 Affinity Capture-Western; Reconstituted Complex
DNMBPDNM111686914506234 Affinity Capture-Western; Reconstituted Complex
FNBP1DNM110809915252009 Affinity Capture-Western
FNBP1DNM111668615252009 Affinity Capture-Western
MED31DNM110809916169070 Two-hybrid
MED31DNM111921116169070 Two-hybrid
PIN4DNM110809916169070 Two-hybrid
PIN4DNM111132016169070 Two-hybrid
KIAA1377DNM110809916169070 Two-hybrid
KIAA1377DNM112161716169070 Two-hybrid
ASB13DNM110809916169070 Two-hybrid
ASB13DNM112286516169070 Two-hybrid
UBASH3ADNM110809917382318 Affinity Capture-Western
UBASH3ADNM111974817382318 Affinity Capture-Western
Gene Symbol Interactant Interaction ID References Description
SH3GL3DNM119476611894096 Endophilin A3 interacts with Dynamin.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:107384
  • Data Attributes: MGI curated and HomoloGene calculated
No data