Gene Symbol:	DNA2 ( DNA2L,FLJ10063,KIAA0083,MGC133297 )
Gene Full Name:	DNA replication helicase 2 homolog (yeast)
Band:	10q21.3
Quick Links	Entrez ID:1763; OMIM: 601810; Uniprot ID:DNA2L_HUMAN; ENSEMBL ID: ENSG00000138346; HGNC ID: 2939
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0000784	ISS	-	nuclear chromosome, telomeric region	23604072
GO:0005634	IDA	-	nucleus	19487465
GO:0005654	TAS	-	nucleoplasm	-
GO:0005739	IDA	-	mitochondrion	-
GO:0005760	IDA	colocalizes_with	gamma DNA polymerase complex	18995831
GO:0042645	IDA	-	mitochondrial nucleoid	19487465

GO ID	Evidence	Qualifier	GO_term	References
GO:0003677	IDA	-	DNA binding	20019387
GO:0003678	IDA	-	DNA helicase activity	16595800
GO:0003678	IDA	NOT	DNA helicase activity	16595799
GO:0004386	TAS	-	helicase activity	18995831
GO:0004518	IDA	-	nuclease activity	21325134
GO:0005515	IPI	-	protein binding	20019387
GO:0005524	IEA	-	ATP binding	-
GO:0016887	TAS	-	ATPase activity	18995831
GO:0016890	IDA	-	site-specific endodeoxyribonuclease activity, specific for altered base	18995831
GO:0017108	IDA	-	5'-flap endonuclease activity	16595799
GO:0043139	IDA	-	5'-3' DNA helicase activity	20019387
GO:0043142	IDA	-	single-stranded DNA-dependent ATPase activity	16595799
GO:0046872	IEA	-	metal ion binding	-
GO:0051539	IEA	-	4 iron, 4 sulfur cluster binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0000076	IMP	-	DNA replication checkpoint	22570476
GO:0000722	TAS	-	telomere maintenance via recombination	-
GO:0000723	ISS	-	telomere maintenance	23604072
GO:0000729	IDA	-	DNA double-strand break processing	21325134
GO:0000731	TAS	-	DNA synthesis involved in DNA repair	-
GO:0000732	TAS	-	strand displacement	-
GO:0006260	IMP	-	DNA replication	22570476
GO:0006260	TAS	-	DNA replication	-
GO:0006264	IDA	-	mitochondrial DNA replication	18995831
GO:0006284	IDA	-	base-excision repair	18995831
GO:0032508	IEA	-	DNA duplex unwinding	-
GO:0033567	IDA	-	DNA replication, Okazaki fragment processing	22570407
GO:0043137	IDA	-	DNA replication, removal of RNA primer	18995831
GO:0043504	IDA	-	mitochondrial DNA repair	19487465
GO:0044806	TAS	-	G-quadruplex DNA unwinding	27918544
GO:0045740	IDA	-	positive regulation of DNA replication	18995831
GO:0090305	ISS	-	nucleic acid phosphodiester bond hydrolysis	23604072
GO:0090656	TAS	-	t-circle formation	27918544
GO:1901796	TAS	-	regulation of signal transduction by p53 class mediator	-
GO:1902990	ISS	-	mitotic telomere maintenance via semi-conservative replication	23604072

AutismKB 2.0

Annotation Details for DNA2