AutismKB 2.0

Annotation Details for DYNC1H1


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Basic Information Top
Gene Symbol:DYNC1H1 ( DHC1,DHC1a,DKFZp686P2245,DNCH1,DNCL,DNECL,DYHC,Dnchc1,HL-3,KIAA0325,p22 )
Gene Full Name: dynein, cytoplasmic 1, heavy chain 1
Band: 14q32.31
Quick LinksEntrez ID:1778; OMIM: 600112; Uniprot ID:DYHC1_HUMAN; ENSEMBL ID: ENSG00000197102; HGNC ID: 2961
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005813IDA-centrosome21399614
GO:0005829TAS-cytosol-
GO:0005868IDA-cytoplasmic dynein complex21723285
GO:0005868NAS-cytoplasmic dynein complex8666668
GO:0005874IDA-microtubule21525035
GO:0016020IDA-membrane19946888
GO:0030175IEA-filopodium-
GO:0031012IDA-extracellular matrix23979707
GO:0035578TAS-azurophil granule lumen-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0005515IPI-protein binding17043677
GO:0005524IEA-ATP binding-
GO:0008569IDAcontributes_toATP-dependent microtubule motor activity, minus-end-directed21723285
GO:0051959IPI-dynein light intermediate chain binding25272277
GO ID Evidence Qualifier GO_term References
GO:0000086TAS-G2/M transition of mitotic cell cycle-
GO:0006888TAS-ER to Golgi vesicle-mediated transport-
GO:0007018IEA-microtubule-based movement-
GO:0007052NAS-mitotic spindle organization8227145
GO:0019886TAS-antigen processing and presentation of exogenous peptide antigen via MHC class II-
GO:0032388IMP-positive regulation of intracellular transport27462074
GO:0033962ISS-cytoplasmic mRNA processing body assembly-
GO:0034063ISS-stress granule assembly-
GO:0043312TAS-neutrophil degranulation-
GO:0051293IMP-establishment of spindle localization23027904
GO:0060236IMP-regulation of mitotic spindle organization23027904
GO:0090235IMP-regulation of metaphase plate congression27462074
GO:0097711TAS-ciliary basal body docking-
GO:1905832IMP-positive regulation of spindle assembly27462074
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DYNC1H1ARF610687717353931 Affinity Capture-MS
DYNC1H1ARF610811717353931 Affinity Capture-MS
DYNC1H1CDC5L10811711101529 Affinity Capture-MS; Co-purification
DYNC1H1CDC5L10742411101529 Affinity Capture-MS; Co-purification
DYNC1H1DCTN110811714600259 Affinity Capture-Western
DYNC1H1DCTN110800714600259 Affinity Capture-Western
EPB41DYNC1H110834910189366 Affinity Capture-Western
EPB41DYNC1H110811710189366 Affinity Capture-Western
NDEL1DYNC1H112352711163260 Affinity Capture-Western
NDEL1DYNC1H110811711163260 Affinity Capture-Western
BICD2DYNC1H111689111483508 Affinity Capture-MS
BICD2DYNC1H110811711483508 Affinity Capture-MS
PAFAH1B1DYNC1H111108511889140 Affinity Capture-Western; Two-hybrid
PAFAH1B1DYNC1H110811711889140 Affinity Capture-Western; Two-hybrid
TOR1ADYNC1H110819317353931 Affinity Capture-MS
TOR1ADYNC1H110811717353931 Affinity Capture-MS
NME2DYNC1H110811717353931 Affinity Capture-MS
NME2DYNC1H111089517353931 Affinity Capture-MS
C20orf24DYNC1H112101517353931 Affinity Capture-MS
C20orf24DYNC1H110811717353931 Affinity Capture-MS
SNRPBDYNC1H111251217353931 Affinity Capture-MS
SNRPBDYNC1H110811717353931 Affinity Capture-MS
TSC22D1DYNC1H111437417353931 Affinity Capture-MS
TSC22D1DYNC1H110811717353931 Affinity Capture-MS
EGFRDYNC1H110811720029029 PCA
EGFRDYNC1H110827620029029 PCA
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:103147
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-7050'