AutismKB 2.0

Annotation Details for DPYD


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Basic Information Top
Gene Symbol:DPYD ( DHP,DHPDHASE,DPD,MGC132008,MGC70799 )
Gene Full Name: dihydropyrimidine dehydrogenase
Band: 1p21.3
Quick LinksEntrez ID:1806; OMIM: 612779; Uniprot ID:DPYD_HUMAN; ENSEMBL ID: ENSG00000188641; HGNC ID: 3012
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm1512248
GO:0005829IDA-cytosol9348115
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding25416956
GO:0017113IDA-dihydropyrimidine dehydrogenase (NADP+) activity1512248
GO:0017113IMP-dihydropyrimidine dehydrogenase (NADP+) activity11988088
GO:0017113ISS-dihydropyrimidine dehydrogenase (NADP+) activity-
GO:0017113TAS-dihydropyrimidine dehydrogenase (NADP+) activity-
GO:0042803IDA-protein homodimerization activity1512248
GO:0042803ISS-protein homodimerization activity-
GO:0046872IEA-metal ion binding-
GO:0050660ISS-flavin adenine dinucleotide binding-
GO:0050661ISS-NADP binding-
GO:0051539IEA-4 iron, 4 sulfur cluster binding-
GO ID Evidence Qualifier GO_term References
GO:0006145IMP-purine nucleobase catabolic process11988088
GO:0006208IMP-pyrimidine nucleobase catabolic process11988088
GO:0006208ISS-pyrimidine nucleobase catabolic process-
GO:0006210IDA-thymine catabolic process10410956
GO:0006212IDA-uracil catabolic process1512248
GO:0006214IDA-thymidine catabolic process1512248
GO:0019483IEA-beta-alanine biosynthetic process-
GO:0046135TAS-pyrimidine nucleoside catabolic process-
GO:0055114IEA-oxidation-reduction process-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2139667
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2459'