Annotation Details for DRD1
Basic Information Top
Gene Symbol: | DRD1 ( DADR,DRD1A ) |
---|---|
Gene Full Name: | dopamine receptor D1 |
Band: | 5q35.2 |
Quick Links | Entrez ID:1812; OMIM: 126449; Uniprot ID:DRD1_HUMAN; ENSEMBL ID: ENSG00000184845; HGNC ID: 3020 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005634 | IEA | - | nucleus | - |
GO:0005789 | IEA | - | endoplasmic reticulum membrane | - |
GO:0005886 | IDA | - | plasma membrane | 11500503 |
GO:0005886 | TAS | - | plasma membrane | - |
GO:0005887 | IC | - | integral component of plasma membrane | 2144334 |
GO:0060170 | IDA | - | ciliary membrane | 20531939 |
GO:0097730 | IDA | - | non-motile cilium | 20531939 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0001588 | IDA | - | dopamine neurotransmitter receptor activity, coupled via Gs | 2144334 |
GO:0001588 | IMP | - | dopamine neurotransmitter receptor activity, coupled via Gs | 1282671 |
GO:0004952 | IDA | - | dopamine neurotransmitter receptor activity | 1831904 |
GO:0005515 | IPI | - | protein binding | 15569306 |
GO:0035240 | IMP | - | dopamine binding | 1282671 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0001659 | IEA | - | temperature homeostasis | - |
GO:0001661 | IEA | - | conditioned taste aversion | - |
GO:0001662 | IEA | - | behavioral fear response | - |
GO:0001963 | IEA | - | synaptic transmission, dopaminergic | - |
GO:0001975 | IEA | - | response to amphetamine | - |
GO:0006606 | IEA | - | protein import into nucleus | - |
GO:0007187 | IDA | - | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | 1282671 |
GO:0007189 | IDA | - | adenylate cyclase-activating G-protein coupled receptor signaling pathway | 2144334 |
GO:0007190 | IDA | - | activation of adenylate cyclase activity | 2168520 |
GO:0007191 | IDA | - | adenylate cyclase-activating dopamine receptor signaling pathway | 2144334 |
GO:0007416 | ISS | - | synapse assembly | - |
GO:0007612 | IBA | - | learning | - |
GO:0007613 | IEA | - | memory | - |
GO:0007617 | ISS | - | mating behavior | - |
GO:0007625 | IEA | - | grooming behavior | - |
GO:0007628 | ISS | - | adult walking behavior | - |
GO:0008542 | ISS | - | visual learning | - |
GO:0010579 | IEA | - | positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway | - |
GO:0010628 | IMP | - | positive regulation of gene expression | 24136195 |
GO:0014002 | IEA | - | astrocyte development | - |
GO:0015872 | IEA | - | dopamine transport | - |
GO:0019226 | ISS | - | transmission of nerve impulse | - |
GO:0019228 | IEA | - | neuronal action potential | - |
GO:0021542 | IEA | - | dentate gyrus development | - |
GO:0021756 | IEA | - | striatum development | - |
GO:0021853 | ISS | - | cerebral cortex GABAergic interneuron migration | - |
GO:0030335 | ISS | - | positive regulation of cell migration | - |
GO:0030432 | IEA | - | peristalsis | - |
GO:0030819 | IDA | - | positive regulation of cAMP biosynthetic process | 1282671 |
GO:0035106 | IEA | - | operant conditioning | - |
GO:0042053 | IEA | - | regulation of dopamine metabolic process | - |
GO:0042311 | IEA | - | vasodilation | - |
GO:0042417 | IC | - | dopamine metabolic process | 8301582 |
GO:0042493 | ISS | - | response to drug | - |
GO:0042711 | IEA | - | maternal behavior | - |
GO:0043268 | ISS | - | positive regulation of potassium ion transport | - |
GO:0046323 | IEA | - | glucose import | - |
GO:0046959 | IEA | - | habituation | - |
GO:0046960 | IEA | - | sensitization | - |
GO:0048148 | IEA | - | behavioral response to cocaine | - |
GO:0051281 | IDA | - | positive regulation of release of sequestered calcium ion into cytosol | 1282671 |
GO:0051482 | IDA | - | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | 1282671 |
GO:0051584 | IC | - | regulation of dopamine uptake involved in synaptic transmission | 8301582 |
GO:0051968 | ISS | - | positive regulation of synaptic transmission, glutamatergic | - |
GO:0060134 | ISS | - | prepulse inhibition | - |
GO:0060158 | IDA | - | phospholipase C-activating dopamine receptor signaling pathway | 1282671 |
GO:0060158 | IGI | - | phospholipase C-activating dopamine receptor signaling pathway | 17194762 |
GO:0060291 | IEA | - | long-term synaptic potentiation | - |
GO:0060292 | IEA | - | long term synaptic depression | - |
GO:0071870 | IDA | - | cellular response to catecholamine stimulus | 18403039 |
GO:1903351 | IMP | - | cellular response to dopamine | 24136195 |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
DRD1 | ADA | 106614 | 12150791 | Co-localization |
DRD1 | ADA | 108146 | 12150791 | Co-localization |
DRD1 | ADORA1 | 106646 | 10890919 | Affinity Capture-Western |
DRD1 | ADORA1 | 108146 | 10890919 | Affinity Capture-Western |
DNAJC14 | DRD1 | 124515 | 11331877 | Reconstituted Complex; Two-hybrid |
DNAJC14 | DRD1 | 108146 | 11331877 | Reconstituted Complex; Two-hybrid |
COPG | DRD1 | 116496 | 11893085 | Affinity Capture-Western; Reconstituted Complex |
COPG | DRD1 | 108146 | 11893085 | Affinity Capture-Western; Reconstituted Complex |
COPG2 | DRD1 | 117926 | 11893085 | Affinity Capture-Western; Reconstituted Complex |
COPG2 | DRD1 | 108146 | 11893085 | Affinity Capture-Western; Reconstituted Complex |
HRH3 | DRD1 | 116416 | 19413572 | FRET |
HRH3 | DRD1 | 108146 | 19413572 | FRET |
No data |
No data |
No data |
Gene Symbol | Poly Names | Gene overview in PDGene |
---|---|---|
DRD1 | DRD1_-48A/G, rs155417, rs1799914, rs4532 | Gene overview in PDGene |
Gene Symbol | Poly Names | Gene overview in SZGene |
---|---|---|
DRD1 | DRD1_2bpSTR, DRD1_4bpSTR, DRD1_EcoRI, rs10063995, rs11746641, rs11749676, rs12518222, rs13306309, rs155417, rs2168631, rs251937, rs265967, rs265981, rs267416, rs267418, rs35916350, rs4532, rs4867798, rs5326, rs5330, rs5331, rs686, rs6882300 | Gene overview in SZGene |
- MGI ID: MGI:99578
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-070524-2