Gene Symbol:	DSG1 ( CDHF4,DG1,DSG,PPKS1,SPPK1 )
Gene Full Name:	desmoglein 1
Band:	18q12.1
Quick Links	Entrez ID:1828; OMIM: 125670; Uniprot ID:DSG1_HUMAN; ENSEMBL ID: ENSG00000134760; HGNC ID: 3048
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0001533	TAS	-	cornified envelope	-
GO:0005829	TAS	-	cytosol	-
GO:0005886	TAS	-	plasma membrane	-
GO:0005911	IDA	colocalizes_with	cell-cell junction	7983064
GO:0009898	IDA	-	cytoplasmic side of plasma membrane	7983064
GO:0016021	IEA	-	integral component of membrane	-
GO:0016324	IEA	-	apical plasma membrane	-
GO:0016328	IEA	-	lateral plasma membrane	-
GO:0030057	NAS	-	desmosome	1711210
GO:0031012	IDA	-	extracellular matrix	23979707
GO:0070062	IDA	-	extracellular exosome	23376485
GO:0101003	TAS	-	ficolin-1-rich granule membrane	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0005509	NAS	-	calcium ion binding	1770008
GO:0005515	IPI	-	protein binding	24965446
GO:0015643	NAS	-	toxic substance binding	12582396
GO:0045295	IPI	-	gamma-catenin binding	7983064

GO ID	Evidence	Qualifier	GO_term	References
GO:0007043	NAS	-	cell-cell junction assembly	12485422
GO:0007156	IEA	-	homophilic cell adhesion via plasma membrane adhesion molecules	-
GO:0016337	NAS	-	single organismal cell-cell adhesion	1711210
GO:0016339	NAS	-	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	1770008
GO:0031424	TAS	-	keratinization	-
GO:0032570	IEA	-	response to progesterone	-
GO:0043312	TAS	-	neutrophil degranulation	-
GO:0050821	IDA	-	protein stabilization	7983064
GO:0060135	IEA	-	maternal process involved in female pregnancy	-
GO:0070268	TAS	-	cornification	-

Gene Symbol	Interactant	Interaction ID	References	Description
DSG1	DSC1	108157	9606214	Reconstituted Complex
DSG1	DSC1	108162	9606214	Reconstituted Complex
DSG1	DSC2	108158	9443898	Affinity Capture-Western
DSG1	DSC2	108162	9443898	Affinity Capture-Western
JUP	DSG1	109931	9606214	Reconstituted Complex
JUP	DSG1	108162	9606214	Reconstituted Complex
PKP1	DSG1	108162	9606214	Reconstituted Complex
PKP1	DSG1	111334	9606214	Reconstituted Complex
PKP2	DSG1	108162	11790773	Affinity Capture-Western; Two-hybrid
PKP2	DSG1	111335	11790773	Affinity Capture-Western; Two-hybrid
PKP3	DSG1	116357	12707304	Affinity Capture-Western; Two-hybrid
PKP3	DSG1	108162	12707304	Affinity Capture-Western; Two-hybrid
SSSCA1	DSG1	108162	17353931	Affinity Capture-MS
SSSCA1	DSG1	115788	17353931	Affinity Capture-MS
KHDRBS2	DSG1	108162	17643375	Affinity Capture-MS
KHDRBS2	DSG1	128436	17643375	Affinity Capture-MS
USP53	DSG1	108162	19615732	Affinity Capture-MS
USP53	DSG1	120020	19615732	Affinity Capture-MS
OTUD4	DSG1	108162	19615732	Affinity Capture-MS
OTUD4	DSG1	120112	19615732	Affinity Capture-MS
USP1	DSG1	113241	19615732	Affinity Capture-MS
USP1	DSG1	108162	19615732	Affinity Capture-MS

AutismKB 2.0

Annotation Details for DSG1