AutismKB 2.0

Annotation Details for DSG2


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Basic Information Top
Gene Symbol:DSG2 ( ARVC10,ARVD10,CDHF5,CMD1BB,HDGC,MGC117034,MGC117036,MGC117037 )
Gene Full Name: desmoglein 2
Band: 18q12.1
Quick LinksEntrez ID:1829; OMIM: 125671; Uniprot ID:DSG2_HUMAN; ENSEMBL ID: ENSG00000046604; HGNC ID: 3049
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001533TAS-cornified envelope-
GO:0005886IDA-plasma membrane17559062
GO:0005886TAS-plasma membrane-
GO:0005911TAS-cell-cell junction8143788
GO:0009986IDA-cell surface19581412
GO:0014704IDA-intercalated disc23381804
GO:0016021IEA-integral component of membrane-
GO:0016324IEA-apical plasma membrane-
GO:0016328IEA-lateral plasma membrane-
GO:0030057IDA-desmosome23381804
GO:0070062IDA-extracellular exosome19199708
GO ID Evidence Qualifier GO_term References
GO:0005509IEA-calcium ion binding-
GO:0050839IPI-cell adhesion molecule binding17559062
GO:0086083IC-cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication16505173
GO ID Evidence Qualifier GO_term References
GO:0002934IMP-desmosome organization16505173
GO:0003165IMP-Purkinje myocyte development16505173
GO:0007155IDA-cell adhesion17559062
GO:0007156IDA-homophilic cell adhesion via plasma membrane adhesion molecules17559062
GO:0031424TAS-keratinization-
GO:0032570IEA-response to progesterone-
GO:0060135IEA-maternal process involved in female pregnancy-
GO:0070268TAS-cornification-
GO:0086073IMP-bundle of His cell-Purkinje myocyte adhesion involved in cell communication16505173
GO:0086091IMP-regulation of heart rate by cardiac conduction16505173
GO:0098911IMP-regulation of ventricular cardiac muscle cell action potential16505173
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DSG2DSC11081639214392 Affinity Capture-Western; Reconstituted Complex
DSG2DSC11081579214392 Affinity Capture-Western; Reconstituted Complex
DSG2DSC210816311853539 Reconstituted Complex
DSG2DSC210815811853539 Reconstituted Complex
JUPDSG21099318749329 10769205 11710948 Affinity Capture-Western; Reconstituted Complex
JUPDSG21081638749329 10769205 11710948 Affinity Capture-Western; Reconstituted Complex
PKP2DSG210816311790773 Affinity Capture-Western
PKP2DSG211133511790773 Affinity Capture-Western
PKP3DSG211635712707304 Affinity Capture-Western; Two-hybrid
PKP3DSG210816312707304 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1196466
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-7531'