AutismKB 2.0

Annotation Details for DTX1


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Basic Information Top
Gene Symbol:DTX1 ( hDx-1 )
Gene Full Name: deltex homolog 1 (Drosophila)
Band: 12q24.13
Quick LinksEntrez ID:1840; OMIM: 602582; Uniprot ID:DTX1_HUMAN; ENSEMBL ID: ENSG00000135144; HGNC ID: 3060
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005737TAS-cytoplasm9590294
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0016604IDA-nuclear body-
GO ID Evidence Qualifier GO_term References
GO:0003713TAS-transcription coactivator activity9590294
GO:0005112IDA-Notch binding11564735
GO:0005515IPI-protein binding7671825
GO:0008270IEA-zinc ion binding-
GO:0016740IEA-transferase activity-
GO:0017124IEA-SH3 domain binding-
GO:0031625IPI-ubiquitin protein ligase binding17028573
GO ID Evidence Qualifier GO_term References
GO:0006351NAS-transcription, DNA-templated11564735
GO:0006366TAS-transcription from RNA polymerase II promoter9590294
GO:0007166TAS-cell surface receptor signaling pathway9590294
GO:0007219TAS-Notch signaling pathway-
GO:0008593IGI-regulation of Notch signaling pathway11564735
GO:0010001IEA-glial cell differentiation-
GO:0016567IEA-protein ubiquitination-
GO:0045581IEA-negative regulation of T cell differentiation-
GO:0045665IGI-negative regulation of neuron differentiation11564735
GO:1903506IEA-regulation of nucleic acid-templated transcription-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GRB2DTX11091429590294 Two-hybrid
GRB2DTX11081739590294 Two-hybrid
DTX1DTX110817311564735 Affinity Capture-Western
NOTCH1DTX111091311564735 Affinity Capture-Western
NOTCH1DTX110817311564735 Affinity Capture-Western
EP300DTX110834711564735 Affinity Capture-Western; Two-hybrid
EP300DTX110817311564735 Affinity Capture-Western; Two-hybrid
DTX3LDTX110817312670957 Affinity Capture-Western
DTX3LDTX112739212670957 Affinity Capture-Western
MAP3K1DTX111037815684388 Affinity Capture-Western; Reconstituted Complex
MAP3K1DTX110817315684388 Affinity Capture-Western; Reconstituted Complex
ITCHDTX110817318628966 Reconstituted Complex
ITCHDTX112374718628966 Reconstituted Complex
UBE2CDTX111624919690564 Two-hybrid
UBE2CDTX110817319690564 Two-hybrid
UBE2UDTX110817319690564 Two-hybrid
UBE2UDTX112715619690564 Two-hybrid
UBE2D4DTX111964119690564 Two-hybrid
UBE2D4DTX110817319690564 Two-hybrid
UBE2D1DTX111316919690564 Two-hybrid
UBE2D1DTX110817319690564 Two-hybrid
UBE2D2DTX111317019690564 Two-hybrid
UBE2D2DTX110817319690564 Two-hybrid
UBE2D3DTX111317119690564 Two-hybrid
UBE2D3DTX110817319690564 Two-hybrid
UBE2E1DTX111317219690564 Two-hybrid
UBE2E1DTX110817319690564 Two-hybrid
UBE2NDTX111318219690564 Two-hybrid
UBE2NDTX110817319690564 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1352744
  • Data Attributes: MGI curated and HomoloGene calculated
No data