Annotation Details for DUSP4
Basic Information Top
| Gene Symbol: | DUSP4 ( HVH2,MKP-2,MKP2,TYP ) |
|---|---|
| Gene Full Name: | dual specificity phosphatase 4 |
| Band: | 8p12 |
| Quick Links | Entrez ID:1846; OMIM: 602747; Uniprot ID:DUS4_HUMAN; ENSEMBL ID: ENSG00000120875; HGNC ID: 3070 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005634 | IDA | - | nucleus | 7535768 |
| GO:0005654 | IDA | - | nucleoplasm | - |
| GO:0005654 | TAS | - | nucleoplasm | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0004725 | IDA | - | protein tyrosine phosphatase activity | 7535768 |
| GO:0004725 | TAS | - | protein tyrosine phosphatase activity | - |
| GO:0008330 | IDA | - | protein tyrosine/threonine phosphatase activity | 7535768 |
| GO:0016791 | IDA | - | phosphatase activity | 24531476 |
| GO:0017017 | IEA | - | MAP kinase tyrosine/serine/threonine phosphatase activity | - |
| GO:1990439 | IDA | - | MAP kinase threonine phosphatase activity | 7535768 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0000188 | IDA | - | inactivation of MAPK activity | 7535768 |
| GO:0001706 | IBA | - | endoderm formation | - |
| GO:0016311 | IDA | - | dephosphorylation | 24531476 |
| GO:0035335 | IDA | - | peptidyl-tyrosine dephosphorylation | 7535768 |
| GO:0035970 | IDA | - | peptidyl-threonine dephosphorylation | 7535768 |
| GO:0070373 | IMP | - | negative regulation of ERK1 and ERK2 cascade | 7535768 |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| DUSP4 | MAPK14 | 108179 | 11387337 | Reconstituted Complex |
| DUSP4 | MAPK14 | 107819 | 11387337 | Reconstituted Complex |
| MAPK3 | DUSP4 | 108179 | 11387337 | Reconstituted Complex |
| MAPK3 | DUSP4 | 111581 | 11387337 | Reconstituted Complex |
| MAPK8 | DUSP4 | 108179 | 11387337 | Reconstituted Complex |
| MAPK8 | DUSP4 | 111585 | 11387337 | Reconstituted Complex |
| No data |
| No data |
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