AutismKB 2.0

Annotation Details for DVL3


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Basic Information Top
Gene Symbol:DVL3 ( KIAA0208 )
Gene Full Name: dishevelled, dsh homolog 3 (Drosophila)
Band: 3q27.1
Quick LinksEntrez ID:1857; OMIM: 601368; Uniprot ID:DVL3_HUMAN; ENSEMBL ID: ENSG00000161202; HGNC ID: 3087
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin21880741
GO:0005829IDA-cytosol23109420
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0002020IPI-protease binding20227366
GO:0005102IPI-receptor binding17030191
GO:0005109IPI-frizzled binding19388021
GO:0005515IPI-protein binding10330181
GO:0008013IDA-beta-catenin binding10644691
GO:0046982IDA-protein heterodimerization activity19137009
GO:0048365IPI-Rac GTPase binding23109420
GO ID Evidence Qualifier GO_term References
GO:0001934IMP-positive regulation of protein phosphorylation20137080
GO:0016055IDA-Wnt signaling pathway10644691
GO:0035556IEA-intracellular signal transduction-
GO:0035567IMP-non-canonical Wnt signaling pathway19137009
GO:0038031ISS-non-canonical Wnt signaling pathway via JNK cascade-
GO:0042493IEA-response to drug-
GO:0043507IMP-positive regulation of JUN kinase activity19137009
GO:0043547IDA-positive regulation of GTPase activity23109420
GO:0045893IDA-positive regulation of transcription, DNA-templated10644691
GO:0050821IGI-protein stabilization26359454
GO:0060070IDA-canonical Wnt signaling pathway17593335
GO:0060070IGI-canonical Wnt signaling pathway18093802
GO:0060070IMP-canonical Wnt signaling pathway20137080
GO:0060071IDA-Wnt signaling pathway, planar cell polarity pathway12805222
GO:0060071NAS-Wnt signaling pathway, planar cell polarity pathway24431302
GO:0090090TAS-negative regulation of canonical Wnt signaling pathway-
GO:0090179IBA-planar cell polarity pathway involved in neural tube closure-
GO:1903827IDA-regulation of cellular protein localization19625296
GO:1904886TAS-beta-catenin destruction complex disassembly-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DVL3CSNK1D10783716189514 Two-hybrid
DVL3CSNK1D10819016189514 Two-hybrid
DVL3CSNK2A110784110806215 Affinity Capture-Western
DVL3CSNK2A110819010806215 Affinity Capture-Western
DVL3CTNNB110788010806215 Affinity Capture-Western
DVL3CTNNB110819010806215 Affinity Capture-Western
DVL3DAB210797112805222 Affinity Capture-Western; Reconstituted Complex
DVL3DAB210819012805222 Affinity Capture-Western; Reconstituted Complex
DVL3DVL110818810330181 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
DVL3DVL110819010330181 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
AXIN1DVL311390912805222 Affinity Capture-Western
AXIN1DVL310819012805222 Affinity Capture-Western
KLHL12DVL312189016189514 16547521 Affinity Capture-Western; Two-hybrid
KLHL12DVL310819016189514 16547521 Affinity Capture-Western; Two-hybrid
PRPF3DVL311457716189514 Affinity Capture-Western; Two-hybrid
PRPF3DVL310819016189514 Affinity Capture-Western; Two-hybrid
DIDO1DVL311626616189514 Two-hybrid
DIDO1DVL310819016189514 Two-hybrid
MYST2DVL311631516189514 Two-hybrid
MYST2DVL310819016189514 Two-hybrid
TNFAIP8L1DVL312597316189514 Two-hybrid
TNFAIP8L1DVL310819016189514 Two-hybrid
DPPA2DVL312740716189514 Two-hybrid
DPPA2DVL310819016189514 Two-hybrid
BAHD1DVL310819016189514 Two-hybrid
BAHD1DVL311655816189514 Two-hybrid
ZBTB48DVL310819016189514 Two-hybrid
ZBTB48DVL310934916189514 Two-hybrid
PITX1DVL311132416189514 Two-hybrid
PITX1DVL310819016189514 Two-hybrid
ZNF408DVL312289416189514 Two-hybrid
ZNF408DVL310819016189514 Two-hybrid
SNX22DVL312294516189514 Two-hybrid
SNX22DVL310819016189514 Two-hybrid
LNX1DVL312421916189514 Two-hybrid
LNX1DVL310819016189514 Two-hybrid
CCNKDVL311433916189514 Two-hybrid
CCNKDVL310819016189514 Two-hybrid
PRICKLE1DVL312683517030191 Affinity Capture-Western
PRICKLE1DVL310819017030191 Affinity Capture-Western
UBCDVL311316417030191 Affinity Capture-Western
UBCDVL310819017030191 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:108100
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-010319-1'