AutismKB 2.0

Annotation Details for E4F1


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Basic Information Top
Gene Symbol:E4F1 ( E4F,MGC99614 )
Gene Full Name: E4F transcription factor 1
Band: 16p13.3
Quick LinksEntrez ID:1877; OMIM: 603022; Uniprot ID:E4F1_HUMAN; ENSEMBL ID: ENSG00000167967; HGNC ID: 3121
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005737IEA-cytoplasm-
GO:0005819IEA-spindle-
GO ID Evidence Qualifier GO_term References
GO:0000977IDA-RNA polymerase II regulatory region sequence-specific DNA binding2169022
GO:0001227IC-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-
GO:0003677TAS-DNA binding10869426
GO:0003700TAS-transcription factor activity, sequence-specific DNA binding9121437
GO:0003713TAS-transcription coactivator activity9121437
GO:0003714TAS-transcription corepressor activity10869426
GO:0005515IPI-protein binding12730668
GO:0016740IEA-transferase activity-
GO:0035497IDA-cAMP response element binding14645522
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter14645522
GO:0006260IEA-DNA replication-
GO:0006351IEA-transcription, DNA-templated-
GO:0008283TAS-cell proliferation10869426
GO:0009794IEA-regulation of mitotic cell cycle, embryonic-
GO:0010564IDA-regulation of cell cycle process14645522
GO:0016032IEA-viral process-
GO:0016567IEA-protein ubiquitination-
GO:0040008IEA-regulation of growth-
GO:0051301IEA-cell division-
GO:0071850TAS-mitotic cell cycle arrest14645522
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
E4F1ATM10820910608806 Protein-peptide
E4F1ATM10696210608806 Protein-peptide
E4F1ATR10820910608806 Protein-peptide
E4F1ATR10702710608806 Protein-peptide
E4F1CDKN2A10820912446718 Affinity Capture-Western; Two-hybrid
E4F1CDKN2A10746312446718 Affinity Capture-Western; Two-hybrid
PRKDCE4F110820910608806 Protein-peptide
PRKDCE4F111157710608806 Protein-peptide
TP53E4F110820910644996 12446718 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TP53E4F111301010644996 12446718 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RB1E4F110820910869426 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RB1E4F111186010869426 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
HDAC1E4F110820912730668 Affinity Capture-Western; Reconstituted Complex
HDAC1E4F110931512730668 Affinity Capture-Western; Reconstituted Complex
EHMT2E4F110820916189514 Two-hybrid
EHMT2E4F111612316189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:109530
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050913-103'