AutismKB 2.0

Annotation Details for NR0B1


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Basic Information Top
Gene Symbol:NR0B1 ( AHC,AHCH,AHX,DAX-1,DAX1,DSS,GTD,HHG,NROB1 )
Gene Full Name: nuclear receptor subfamily 0, group B, member 1
Band: Xp21.2
Quick LinksEntrez ID:190; OMIM: 300473; Uniprot ID:NR0B1_HUMAN; ENSEMBL ID: ENSG00000169297; HGNC ID: 7960
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus7990953
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005737IDA-cytoplasm16709599
GO:0016020IDA-membrane10848616
GO:0042788IDA-polysomal ribosome10848616
GO ID Evidence Qualifier GO_term References
GO:0003677IDA-DNA binding7990953
GO:0003707IEA-steroid hormone receptor activity-
GO:0003714IMP-transcription corepressor activity19651776
GO:0003723IDA-RNA binding10848616
GO:0004879IDA-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding7990953
GO:0004879NAS-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding9384387
GO:0005515IPI-protein binding12771131
GO:0008134IPI-transcription factor binding19651776
GO:0019904IPI-protein domain specific binding15100213
GO:0032448IDA-DNA hairpin binding9384387
GO:0035258IPI-steroid hormone receptor binding11875111
GO:0042803IPI-protein homodimerization activity16709599
GO:0043565IDA-sequence-specific DNA binding9384387
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0006367TAS-transcription initiation from RNA polymerase II promoter-
GO:0006694IDA-steroid biosynthetic process9384387
GO:0007283IEA-spermatogenesis-
GO:0008104IDA-protein localization11875111
GO:0008406IMP-gonad development7990953
GO:0008584IMP-male gonad development7990958
GO:0021854NAS-hypothalamus development15464421
GO:0021983NAS-pituitary gland development15464421
GO:0030238IEA-male sex determination-
GO:0030325IMP-adrenal gland development7990953
GO:0030522IEA-intracellular receptor signaling pathway-
GO:0033144IDA-negative regulation of intracellular steroid hormone receptor signaling pathway11875111
GO:0033327IEA-Leydig cell differentiation-
GO:0035902IEA-response to immobilization stress-
GO:0043401IEA-steroid hormone mediated signaling pathway-
GO:0043433IMP-negative regulation of sequence-specific DNA binding transcription factor activity19651776
GO:0045596IEA-negative regulation of cell differentiation-
GO:0045892IDA-negative regulation of transcription, DNA-templated7990953
GO:0045892IMP-negative regulation of transcription, DNA-templated19651776
GO:0060008IEA-Sertoli cell differentiation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
COPS2NR0B110669510713076 Reconstituted Complex; Two-hybrid
COPS2NR0B111472910713076 Reconstituted Complex; Two-hybrid
NR5A1NR0B110669511459805 11713202 Reconstituted Complex; Two-hybrid
NR5A1NR0B110879211459805 11713202 Reconstituted Complex; Two-hybrid
NRIP1NR0B110669511459805 Reconstituted Complex; Two-hybrid
NRIP1NR0B111384311459805 Reconstituted Complex; Two-hybrid
SREBF1NR0B110669511713202 Reconstituted Complex; Two-hybrid
SREBF1NR0B111259811713202 Reconstituted Complex; Two-hybrid
ARNR0B110669511875111 12771131 Affinity Capture-Western
ARNR0B110686211875111 12771131 Affinity Capture-Western
PGRNR0B111126012771131 Affinity Capture-Western; Reconstituted Complex
PGRNR0B110669512771131 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1352460
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070130-1'