AutismKB 2.0

Annotation Details for EEF2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:EEF2 ( EEF-2,EF2 )
Gene Full Name: eukaryotic translation elongation factor 2
Band: 19p13.3
Quick LinksEntrez ID:1938; OMIM: 130610; Uniprot ID:EF2_HUMAN; ENSEMBL ID: ENSG00000167658; HGNC ID: 3214
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005634IDA-nucleus21630459
GO:0005737IDA-cytoplasm25064856
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane-
GO:0016020IDA-membrane19946888
GO:0016235IDA-aggresome-
GO:0030529IDA-intracellular ribonucleoprotein complex18809582
GO:0031012IDA-extracellular matrix23979707
GO:0034774TAS-secretory granule lumen-
GO:0042788IEA-polysomal ribosome-
GO:0045121IEA-membrane raft-
GO:0070062IDA-extracellular exosome19056867
GO:1904813TAS-ficolin-1-rich granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0002039IEA-p53 binding-
GO:0003723IDA-RNA binding22658674
GO:0003746IEA-translation elongation factor activity-
GO:0003924IEA-GTPase activity-
GO:0005515IPI-protein binding19417104
GO:0005525IEA-GTP binding-
GO:0008097IEA-5S rRNA binding-
GO:0019901IPI-protein kinase binding23823123
GO:0043022IEA-ribosome binding-
GO:0045296IDA-cadherin binding25468996
GO:0051015IEA-actin filament binding-
GO ID Evidence Qualifier GO_term References
GO:0002244IEA-hematopoietic progenitor cell differentiation-
GO:0002931IEA-response to ischemia-
GO:0003009IEA-skeletal muscle contraction-
GO:0006414TAS-translational elongation-
GO:0006479TAS-protein methylation-
GO:0007568IEA-aging-
GO:0014009IEA-glial cell proliferation-
GO:0017183TAS-peptidyl-diphthamide biosynthetic process from peptidyl-histidine-
GO:0032355IEA-response to estradiol-
GO:0034976IEA-response to endoplasmic reticulum stress-
GO:0035914IEA-skeletal muscle cell differentiation-
GO:0042493IEA-response to drug-
GO:0042542IEA-response to hydrogen peroxide-
GO:0043312TAS-neutrophil degranulation-
GO:0045471IEA-response to ethanol-
GO:0045727IMP-positive regulation of translation23184662
GO:0051593IEA-response to folic acid-
GO:1990416IEA-cellular response to brain-derived neurotrophic factor stimulus-
GO:2000767IEA-positive regulation of cytoplasmic translation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TP53EEF211301012891704 Affinity Capture-Western
TP53EEF210825812891704 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:95288
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-5128'