AutismKB 2.0

Annotation Details for EFNA5


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Basic Information Top
Gene Symbol:EFNA5 ( AF1,EFL5,EPLG7,GLC1M,LERK7,RAGS )
Gene Full Name: ephrin-A5
Band: 5q21.3
Quick LinksEntrez ID:1946; OMIM: 601535; Uniprot ID:EFNA5_HUMAN; ENSEMBL ID: ENSG00000184349; HGNC ID: 3225
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005604IEA-basement membrane-
GO:0005886ISS-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0005901IEA-caveola-
GO:0005912IEA-adherens junction-
GO:0031362IDA-anchored component of external side of plasma membrane11870224
GO ID Evidence Qualifier GO_term References
GO:0005168NAS-neurotrophin TRKA receptor binding19036963
GO:0005169NAS-neurotrophin TRKB receptor binding19036963
GO:0005170NAS-neurotrophin TRKC receptor binding19036963
GO:0030297NAS-transmembrane receptor protein tyrosine kinase activator activity19036963
GO:0045499IEA-chemorepellent activity-
GO:0046875IPI-ephrin receptor binding11870224
GO ID Evidence Qualifier GO_term References
GO:0001934NAS-positive regulation of protein phosphorylation19036963
GO:0006915IDANOTapoptotic process11870224
GO:0007171IEA-activation of transmembrane receptor protein tyrosine kinase activity-
GO:0007399TAS-nervous system development9245480
GO:0022407IDA-regulation of cell-cell adhesion11870224
GO:0022604IDA-regulation of cell morphogenesis23242526
GO:0031290IEA-retinal ganglion cell axon guidance-
GO:0032956IDA-regulation of actin cytoskeleton organization11870224
GO:0043087IDA-regulation of GTPase activity11870224
GO:0043087ISS-regulation of GTPase activity-
GO:0048013IDA-ephrin receptor signaling pathway11870224
GO:0048013TAS-ephrin receptor signaling pathway-
GO:0048668IEA-collateral sprouting-
GO:0048672IEA-positive regulation of collateral sprouting-
GO:0050731ISS-positive regulation of peptidyl-tyrosine phosphorylation-
GO:0050919IEA-negative chemotaxis-
GO:0051893IDA-regulation of focal adhesion assembly11870224
GO:0051965IEA-positive regulation of synapse assembly-
GO:0061178ISS-regulation of insulin secretion involved in cellular response to glucose stimulus-
GO:0070507IDA-regulation of microtubule cytoskeleton organization11870224
GO:0071372IEA-cellular response to follicle-stimulating hormone stimulus-
GO:1900025IDA-negative regulation of substrate adhesion-dependent cell spreading23242526
GO:1904322IEA-cellular response to forskolin-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
EPHA3EFNA51083569195962 9245480 Co-fractionation; Reconstituted Complex
EPHA3EFNA51082669195962 9245480 Co-fractionation; Reconstituted Complex
EPHB1EFNA51083619245480 Reconstituted Complex
EPHB1EFNA51082669245480 Reconstituted Complex
EPHA7EFNA510835910366629 Affinity Capture-Western
EPHA7EFNA510826610366629 Affinity Capture-Western
GRIP1EFNA510826617631495 Reconstituted Complex
GRIP1EFNA511699517631495 Reconstituted Complex
SRCEFNA511259217631495 Reconstituted Complex
SRCEFNA510826617631495 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
EFNA5rs10074258, rs12654281, rs12657273 Gene overview in AlzGene
Gene Symbol Poly Names Gene overview in PDGene
EFNA5rs153690 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:107444
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-001128-1'