AutismKB 2.0

Annotation Details for EIF4B


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Basic Information Top
Gene Symbol:EIF4B ( EIF-4B,PRO1843 )
Gene Full Name: eukaryotic translation initiation factor 4B
Band: 12q13.13
Quick LinksEntrez ID:1975; OMIM: 603928; Uniprot ID:IF4B_HUMAN; ENSEMBL ID: ENSG00000063046; HGNC ID: 3285
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0005844IBA-polysome-
GO:0016281TAS-eukaryotic translation initiation factor 4F complex2390971
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0003743IBA-translation initiation factor activity-
GO:0004386TAS-helicase activity-
GO:0005515IPI-protein binding21044950
GO:0033592IBA-RNA strand annealing activity-
GO:0034057IBA-RNA strand-exchange activity-
GO:0043024IBA-ribosomal small subunit binding-
GO ID Evidence Qualifier GO_term References
GO:0000289TAS-nuclear-transcribed mRNA poly(A) tail shortening-
GO:0001731IBA-formation of translation preinitiation complex-
GO:0002181IBA-cytoplasmic translation-
GO:0006413TAS-translational initiation-
GO:0006446TAS-regulation of translational initiation2390971
GO:0097010IBA-eukaryotic translation initiation factor 4F complex assembly-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
EIF4BALK10673914968112 Affinity Capture-MS
EIF4BALK10829114968112 Affinity Capture-MS
EIF3AEIF4B1142108816444 Affinity Capture-Western; Far Western
EIF3AEIF4B1082918816444 Affinity Capture-Western; Far Western
EIF4BEIF4B1082918816444 Far Western; Two-hybrid
PABPC1EIF4B11793911274152 Reconstituted Complex
PABPC1EIF4B10829111274152 Reconstituted Complex
EIF3BEIF4B11421116286006 Affinity Capture-Western
EIF3BEIF4B10829116286006 Affinity Capture-Western
USP7EIF4B11362219615732 Affinity Capture-MS
USP7EIF4B10829119615732 Affinity Capture-MS
USP11EIF4B11386619615732 Affinity Capture-MS
USP11EIF4B10829119615732 Affinity Capture-MS
EIF3FEIF4B11421419615732 Affinity Capture-MS
EIF3FEIF4B10829119615732 Affinity Capture-MS
KBTBD7EIF4B12387320562859 Affinity Capture-MS
KBTBD7EIF4B10829120562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:95304
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-8563'