Annotation Details for EIF5
Basic Information Top
| Gene Symbol: | EIF5 ( EIF-5A ) |
|---|---|
| Gene Full Name: | eukaryotic translation initiation factor 5 |
| Band: | 14q32.32 |
| Quick Links | Entrez ID:1983; OMIM: 601710; Uniprot ID:IF5_HUMAN; ENSEMBL ID: ENSG00000100664; HGNC ID: 3299 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005634 | IDA | NOT | nucleus | 12426392 |
| GO:0005737 | IDA | - | cytoplasm | 12426392 |
| GO:0005829 | IDA | - | cytosol | - |
| GO:0005829 | NAS | - | cytosol | 8663286 |
| GO:0005829 | TAS | - | cytosol | - |
| GO:0005886 | IDA | - | plasma membrane | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0003723 | IDA | - | RNA binding | 22681889 |
| GO:0003743 | NAS | - | translation initiation factor activity | 8663286 |
| GO:0003924 | TAS | - | GTPase activity | 8663286 |
| GO:0005515 | IPI | - | protein binding | 24658146 |
| GO:0005525 | IEA | - | GTP binding | - |
| GO:0008135 | TAS | - | translation factor activity, RNA binding | 8663286 |
| GO:0045296 | IDA | - | cadherin binding | 25468996 |
| GO:0071074 | IEA | - | eukaryotic initiation factor eIF2 binding | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0001731 | IEA | - | formation of translation preinitiation complex | - |
| GO:0006413 | NAS | - | translational initiation | 8663286 |
| GO:0006446 | IDA | - | regulation of translational initiation | 22156057 |
| GO:0090630 | IEA | - | activation of GTPase activity | - |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| EIF3G | EIF5 | 108298 | 9973622 | Affinity Capture-Western |
| EIF3G | EIF5 | 114215 | 9973622 | Affinity Capture-Western |
| EIF2S2 | EIF5 | 114411 | 10805737 | Reconstituted Complex |
| EIF2S2 | EIF5 | 108298 | 10805737 | Reconstituted Complex |
| DDA1 | EIF5 | 122485 | 20562859 | Affinity Capture-MS |
| DDA1 | EIF5 | 108298 | 20562859 | Affinity Capture-MS |
| No data |
| No data |



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