Annotation Details for AIF1
Basic Information Top
| Gene Symbol: | AIF1 ( AIF-1,IBA1,IRT-1,IRT1 ) |
|---|---|
| Gene Full Name: | allograft inflammatory factor 1 |
| Band: | 6p21.33 |
| Quick Links | Entrez ID:199; OMIM: 601833; Uniprot ID:AIF1_HUMAN; ENSEMBL ID: ENSG00000204472; HGNC ID: 352 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0001891 | ISS | - | phagocytic cup | - |
| GO:0005634 | IDA | - | nucleus | 22116621 |
| GO:0005634 | ISS | - | nucleus | - |
| GO:0005737 | ISS | - | cytoplasm | - |
| GO:0005829 | IDA | - | cytosol | 22116621 |
| GO:0005884 | IDA | colocalizes_with | actin filament | 18699778 |
| GO:0030027 | ISS | - | lamellipodium | - |
| GO:0032587 | IDA | colocalizes_with | ruffle membrane | 18699778 |
| GO:0043204 | IEA | - | perikaryon | - |
| GO:0048471 | IDA | - | perinuclear region of cytoplasm | 9614071 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0003674 | ND | - | molecular_function | - |
| GO:0005509 | ISS | - | calcium ion binding | 17011575 |
| GO:0051015 | IDA | - | actin filament binding | 16049345 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0001774 | NAS | - | microglial cell activation | 17011575 |
| GO:0001934 | IEA | - | positive regulation of protein phosphorylation | - |
| GO:0006911 | ISS | - | phagocytosis, engulfment | - |
| GO:0006954 | ISS | - | inflammatory response | - |
| GO:0006954 | NAS | - | inflammatory response | 7769138 |
| GO:0010629 | IEA | - | negative regulation of gene expression | - |
| GO:0014739 | IEA | - | positive regulation of muscle hyperplasia | - |
| GO:0016601 | ISS | - | Rac protein signal transduction | - |
| GO:0030041 | IDA | - | actin filament polymerization | 16049345 |
| GO:0031668 | IEA | - | cellular response to extracellular stimulus | - |
| GO:0032870 | IEA | - | cellular response to hormone stimulus | - |
| GO:0042102 | IDA | - | positive regulation of T cell proliferation | 16049345 |
| GO:0043066 | IEA | - | negative regulation of apoptotic process | - |
| GO:0045429 | IEA | - | positive regulation of nitric oxide biosynthetic process | - |
| GO:0048661 | IDA | - | positive regulation of smooth muscle cell proliferation | 15117732 |
| GO:0048662 | IDA | - | negative regulation of smooth muscle cell proliferation | 9614071 |
| GO:0048678 | IEA | - | response to axon injury | - |
| GO:0051017 | IDA | - | actin filament bundle assembly | 18699778 |
| GO:0051384 | IEA | - | response to glucocorticoid | - |
| GO:0051602 | IEA | - | response to electrical stimulus | - |
| GO:0071315 | IEA | - | cellular response to morphine | - |
| GO:0071346 | IEP | - | cellular response to interferon-gamma | 9614071 |
| GO:0071346 | ISS | - | cellular response to interferon-gamma | - |
| GO:0071447 | IEA | - | cellular response to hydroperoxide | - |
| GO:0071672 | IDA | - | negative regulation of smooth muscle cell chemotaxis | 22116621 |
| GO:0071673 | IDA | - | positive regulation of smooth muscle cell chemotaxis | 22116621 |
| GO:0090026 | IDA | - | positive regulation of monocyte chemotaxis | 15117732 |
| GO:0097178 | ISS | - | ruffle assembly | - |
| GO:0097178 | NAS | - | ruffle assembly | 17011575 |
| GO:1900087 | IDA | - | positive regulation of G1/S transition of mitotic cell cycle | 11557666 |
| GO:2000406 | IDA | - | positive regulation of T cell migration | 16049345 |
Protein-Protein Interaction| No data |
| No data |
| Gene Symbol | Poly Names | Gene overview in SZGene |
|---|---|---|
| AIF1 | rs2857700, rs3132451 | Gene overview in SZGene |